64results about How to "Promote the efficacy of the drug" patented technology

The invention relates to a polymer composition loaded with a sirolimus compound or its derivative. The composition can have diversified forms. A necessary link includes preparing the sirolimus compound or its derivative and a polymer carrier into a micelle. Then according to needs, the micelle can be further prepared into a freeze-dried composition by a freeze-drying technology, or the micelle and other polymer and carrier can be prepared into a solid or semi-solid preparation. The polymer composition can be used for treating tumors, reducing rejection reactions after organ and tissue transplantation, promoting cell regeneration and repair, preventing excessive scar tissue growth after injury and preventing vascular restenosis and blood coagulation embolism, treating or inhibiting autoimmune diseases, and treating or inhibiting inflammation, etc.

The invention relates to an ephedra and bitter apricot kernel cough capsule. The capsule is prepared from the following raw materials in parts by weight: 700-1100 parts of ephedra, 500-800 parts of bitter apricot kernel, 1500-2000 parts of honeysuckle, 500-800 parts of fritillaria cirrhosa, 500-800 parts of radix stemonae, 500-800 parts of platycodon grandiflorum and 400-600 parts of liquorice. The ephedra and bitter apricot kernel cough capsule has the characteristics of being high in bioavailability, quick to release, small in toxic and side effects, high in drug content, small in dose, and convenient to carry.

The invention provides a medical composite containing pirfenidone, which is characterized by containing 20-90% of pirfenidone, 10-50% of filler, 1-10% of disintegrating agent, 0.1-8% of adhesive and 0.2-3% of lubricant.

The invention relates to a dermatological smearing device, which solves the problem that the dermatology treatment is troublesome and easy to cause cross infection when the drug is applied in a largearea. The device comprises a casing, wherein a downward push rod is arranged in the casing, a first medicine bottle is arranged below the push rod, a first medicine feeding tube is fixedly connected below the casing, and a taper liquid outlet is inserted into the first medicine feeding tube for fixation, the outer side of the first medicine feeding tube is provided with a protection cylinder body,and the protection cylinder body is fixedly connected with the casing, the lower end of the first medicine feeding tube is screwed and fixedly connected with a second medicine feeding tube, and the second medicine feeding tube is provided with a clamping device, the clamping device is rotatable, the clamping device is provided with a smearing wheel, and the smearing wheel is arranged below the second medicine feeding tube. The dermatological smearing device improves the effect of the medicine; saves time and labor, has flexible operation, high efficiency, less failure and reusability, and improves the working efficiency for the medical staff.

The present invention is one new kind of precursor micelle preparation and its production process and usage. The precursor micelle preparation contains main medicine, solvent, surfactant and supplementary material. The production process includes the steps of dissolving the main medicine in solvent, adding surfactant, and mixing to obtain the precursor micelle preparation. Or, the production process includes the steps of dissolving the main medicine in volatile solvent, adding the surfactant into the solution, and volatizing the solvent to obtain the precursor micelle preparation. The usage of the precursor micelle preparation includes diluting in water for hydration, dissolving carrier material and forming micelle automatically. The precursor micelle preparation of the present invention may be applied widely in agriculture, chemical industry, food and other fields.

The invention belongs to the technical field of pesticide compounding and particularly relates to fenobucarb-containing water dispersible granules and an application, wherein the weight ratio of tebufenozide to fenobucarb is (15:1)-(1:5). Compared with a single dose, the fenobucarb-containing water dispersible granules delay the generation of pesticide resistance of pests, enlarge the control spectrum of effective activity, improve the effect obviously to reduce the consumption of the pesticide, and reduce the degree of influence to the environment and the pesticide residue while reducing the pesticide use cost of farmers.

The invention belongs to the pesticide field and relates to corn field weedicide composition. The corn field weedicide composition is corn field weedicide preparation compounded by active ingredients of amicarbazone and s-metolachlor and safener benoxacor. In the composition, the weight ratio of amicarbazone to s-metolachlor is (0.5-6):1, and content of benoxacor is 0.5-2% of the total quantity. The composition disclosed by the invention has synergistic effect, expands weed-controlling spectrum and delays development of resistance, dosage is reduced, and safety is improved.

The invention discloses an adefovir dipivoxil composition and a preparation method thereof. The adefovir dipivoxil composition is prepared from the following components in percentage by weight: 5-15% of adefovir dipivoxil, 20-80% of filler, 4-15% of a disintegrating agent, 0-5% of a surfactant, 0-5% of a lubricant, and 1-10% of a coating material. The preparation method is implemented through carrying out direct tabletting or dry granulation and tabletting on raw materials and supplementary materials. The adefovir dipivoxil composition prepared by using the method disclosed by the invention is reliable in quality, stable in properties, simple in production process and low in cost, and satisfies the requirements of preparation mass-production.

The invention provides a traditional Chinese medicine combination for external application for treating arthritis. The traditional Chinese medicine combination comprises, by weight, 13-17 parts of tetradium ruticarpum, 13-17 parts of semen brassicae, 13-17 parts of perillaseed, 13-17 parts of semen raphani, 13-17 parts of pseudo-ginseng and 26-34 parts of coarse salt. The invention further provides a traditional Chinese medicine pack comprising the traditional Chinese medicine combination. The traditional Chinese medicine combination and the traditional Chinese medicine pack have the advantage that the traditional Chinese medicine combination is simple in composition, low in cost, convenient to use, good in efficacy and low in toxic or side effect.

The present invention discloses one kind of instant ant tablet prepared with ant as main component. The preparation process includes the following steps: 1. decocting ant for 1-3 times, merging decoction and filtering; 2. concentrating the decoction to form ropy liquid of relative density 1.05-1.35; 3. mixing the ropy liquid with starch, drying, crushing to 80-160 mesh and sieving; and 4. mixing the fine powder with supplementary material, superfine crushing, 200-300 mesh sieving, pelletizing, low temperature drying and tabletting. The instant ant tablet can disintegrate in water fast for leaching out and taking effect in high bioavailability, and is easy to take, especially for those with dysphagia.

The invention relates to a medicine for treating diabetes and its preparation method, wherein the medicine is prepared from rhizoma dioscoreae, American ginseng, root of Chinese trichosannthes, cornus officinalis, safflower, root of red rooted saliva, lychee seed, chicken's gizzard-skin, astragalus root, fragrant solomonseal rhizome, dried rehmannia root, beach silvertop root, anemarrhena rhizome, lilyturf root, mango leaves, guava leaves and menthol.

The invention discloses a polyurethane antibacterial and anti-tinea pedis insole, which belongs to the field of insole. The insole of the invention has a three-layer structure, the upper layer is a breathable mesh cloth, the middle layer is a polyurethane soft foam layer mixed with traditional Chinese medicine powder, the lower layer is a pure polyurethane layer, and the three layers are bonded together in sequence; the breathable mesh cloth is a honeycomb layer. Reticular air-permeable mesh cloth, the polyurethane soft foam layer is a microporous polyurethane foam material, the traditional Chinese medicine powder is a mixture of meduo monk powder, keel powder and calamine powder, and the pure polyurethane layer is closed-cell polyurethane foam. Material; the thickness ratio of the upper layer, the middle layer and the lower layer is 0.5~0.8:2~3:1~2. The insole provided by the invention has the advantages of simple structure, good air permeability and good antibacterial performance, and is a polyurethane antibacterial and anti-tinea pedis insole which can prevent and treat ringworm, has soft texture and low cost.

The invention relates to an apparatus for treating cervical vertebra and lumbar vertebra and a preparation method thereof. The apparatus comprises a housing in direct contact with human body and a heating unit arranged inside the housing, and the apparatus is characterized in that the housing is made of Mao bamboo of which the external green peel is removed and which is subject to digestion treatment of a Chinese traditional medicine liquid made from the following raw materials by weight: 1g of negundo chastetree bud, 0.75kg of Indian stringbush root and 50kg of water. The preparation method comprises steps of selecting bamboo blocks, digestion and softening treatment of the bamboo blocks, drying in the shade, digestion treatment by the Chinese traditional medicine liquid, assembling and the like. The apparatus has significant short-term remission effects on pains of cervical vertebra, lumbar vertebra and back, and solidified and durative treatment effect can be obtained by a longer period of treatment, and at the same time the apparatus is characterized by being not easy to cause tolerance. The preparation method is characterized by simpleness, easy materials, low manufacturing cost, and natural environment protection.

The invention relates to health care tea and a preparation method thereof, in particular to medicinal spring lung-moistening tea and a preparation method thereof. The medicinal spring lung-moistening tea is prepared from the following raw materials in part by weight: 40 to 70 parts of red maple leaves, 15 to 30 parts of green tea, 5 to 10 parts of tangerine peel, 2 to 5 parts of honeysuckle and 1 to 4 parts of perilla, wherein the red maple leaves are red autumn leaves. The method for preparing the medicinal spring lung-moistening tea comprises the following steps of: (1) treating each raw material respectively. mixing according to the matched dosage, grinding the materials, and preparing tea bags for use; and (2) treating each raw material respectively and decocting according to the matched dosage. By taking the red maple leaves as a monarch medicament and combining auxiliary effects of other medicinal components, the medicinal spring lung-moistening tea fully achieves the effects of clearing and nourishing the lung, has the advantages of comprehensive effect on lung health care, strong tea aroma and convenient drinking, and is an optimal choice for daily lung health care.

The invention relates to a pharmaceutical composition used for treating cold and cough and capable of activating blood circulation to dissipate blood stasis, and a preparation method thereof, belonging to the field of traditional Chinese medicines. The pharmaceutical composition is prepared from the following raw materials by weight: 10 to 20 parts of extract of Wikstroemia monnula, 18 to 25 parts of Nicandra physalodes, 10 to 18 parts of Cnicus benedictus, 2 to 5 parts of Catharanthus roseus, 15 to 20 parts of Nigella damascena, 3 to 6 parts of Hyssopus officinalis, 5 to 8 parts of Indigofera tinctoria, 10 to 15 parts of aster root, 8 to 12 parts of Radix Stemonae, 12 to 16 parts of Althaea officinalis root, 6 to 10 parts of balloonflower root, 3 to 6 parts of Rhizoma Menispermi, 6 to 9 parts of spore of common clubmoss, 6 to 9 parts of Mauritius papeda, 7 to 11 parts of mulberry leaf, 6 to 10 parts of Oldenlandia diffusa, 10 to 12 parts of mint and 8 to 20 parts of licorice root. The pharmaceutical composition has substantial curative effect on treatment of cold and cough and on activation of blood circulation for dissipation of blood stasis, treats cold and cough through activation of blood circulation and dissipation of blood stasis, is fast in action and short in curing time, fundamentally treats cold and cough and allows cold and cough not to recur.

The invention puts forward a manufacture technology for an eye mask capable of alleviating dry eyes, eye irritation and asthenopia. The manufacture technology comprises the following steps of: S1: weighing stigma croci, fructus lycii, radix achyranthis bidentatae, fructus tribuli, fructus polygoni orientalis, semen cassia and flos chrysanthemi, and drying the above medicines; S2: placing dried medicines in S1 in a low-temperature storage device, carrying out low-temperature wall breaking for 24h, taking out the medicines, and cooling to a normal temperature; S3: putting medicines cooled in S2in distilled water, dipping for 0.5-2h, and heating to 100DEG C; S4: taking out medicines in S3, putting in a pressure change storage device, and carrying out vacuum wall breaking extraction to obtainextraction liquor; S5: taking out the extraction liquor in S4, and adding borneol for dissolving; and S6: taking out a medicine liquid, adding laurocapram water molecule skin penetrant, adding an emulsifier for stirring, fully mixing water and oil, taking out a mixture after 2h, and blending the eye mask according to a ratio. The eye mask has tiny extraction molecules, can be easily dissolved inwater, and can be fully absorbed.

The present invention relates to a potato seed coating agent, which comprises, by weight, 1-3% of a plant growth regulator sodium nitrophenolate, 1-3% of a plant growth regulator Q-sodium naphthalene acetate, and the balance of water.

The present invention discloses a dispersible tablet made from ants serving as the essential component. The preparation method comprises the steps that: (1) ants are put into an oven which is vacuumized. The ants are sufficiently dried below 80 DEG C; or the ants are frozen to brittle point or below the temperature of vitreous body; then the ants are milled into powder with a particle size ranging from 300 to 600 meshes; (2) the ant power is mixed with a proper amount of auxiliary product and filtered by a screen with a filtering capacity ranging from 80 to 100 meshes; The power is moisturized and pressed into tablets which are dried at low temperature (3) the auxiliary materials mentioned in (2) can be two or more mixtures of starch, dextrin, microcrystalline cellulose and other auxiliary materials. The dispersible tablets made from ants is short in disintegration time in water, rapid in dissolve, good in drug effect exertion, high in bioavailability. The dispersible tablets can be easily swallowed by the elder and patient. The dispersible tablets can be timely and conveniently taken.

The invention discloses a method for preparing enteric stone-like omphalia for treating cancers. The preparation method comprises the following steps: performing ultrasonic cleaning on fresh high-quality stone-like omphalia in a sodium bicarbonate solution; drying the cleaned stone-like omphalia in a fume hook; slicing the dried stone-like omphalia, putting the sliced stone-like omphalia into a container, immersing with a sodium chloride solution, and drying to obtain dried stone-like omphalia; crushing the stone-like omphalia to obtain stone-like omphalia fine powder; granulating with certain auxiliary materials by adopting a dynamic extraction low-temperature concentration process; tabletting, and taking film coating for enteric medicines as a coating material. The traditional Chinese medicine is sclerotium of polyporaceae omphalialapidescens, massive clinical tests prove that the enteric coated stone-like omphalia has the effects of softening hard mass and removing tumor, and reducing lumps, can be used for promoting a human body to restore the capability of synthesizing albumin and increasing immunity, has the effects of relieving dysuria and relaxing, is good in effect, and adopts the enteric coating material to ensure that the stone-like omphalia is not dissolved in stomach and is dissolved and absorbed in small intestine, so that the drug effect can be better played, and the stomach can be protected.

The invention relates to a nicosulfuron soluble granule and a preparation method of the nicosulfuron soluble granule. The nicosulfuron soluble granule is prepared from the following components in percentage by weight: 1%-70% of nicosulfuron, 0.5%-30% of alkali compound, and the balance of agricultural preparation auxiliary elements. The preparation method for the nicosulfuron soluble granule comprises the steps of preparing the raw materials; uniformly mixing ethanol with penetrating agent for later use; crushing and mixing the raw materials; squeezing, pelleting, drying and sieving the raw materials. Due to the nicosulfuron soluble granule, the difficulty that a soluble granule is difficult to prepare as the nicosulfuron is difficult to solve in water is overcome. Compared with a dispersible oil suspension, the content of active ingredients is increased; the dosage in a unit area is reduced; a large quantity of packaging materials, transportation cost and storage space can be saved, no organic solvent is used; and the production cost is greatly lowered. Moreover, the prepared soluble granule has good water solubility, and is beneficial to bringing pesticide effects into play.