Brain region function positioning method based on multimode magnetic resonance imaging

Abstract

The invention discloses a brain region function personalized positioning method based on multimode magnetic resonance imaging. The method adopts a multimode magnetic resonance imaging way and comprises structure magnetic resonance imaging, function magnetic resonance imaging and dispersion magnetic resonance imaging, comprehensively studies the three aspects of the cortex gyrus form, the function task participation brain region and white matter fiber connected therewith, and accurately performs personalized function region positioning of a specific brain region. The method disclosed by the invention can be applied to many studies of clinical nerve and mental science, and comprises the target region positioning of clinical transcranial magnetic stimulation, operation planning and prognosis of the stroke (tumor) patient, the region-of-interest calibration in brain nerve and mental science study, and the like. Since the method comprehensively studies the cortex structure, the function task brain region coarse positioning and the white matter fiber distribution connected therewith for the tested individuals, the limitation of the traditional brain region template based on a unified structure is fundamentally overcome.

Description

technical field [0001] The invention belongs to the fields of medical equipment, medical image processing and neuroimaging, in particular to a brain region function positioning method based on multimodal magnetic resonance imaging. Background technique [0002] In the diagnosis and treatment of neuropsychiatric diseases in neuroscience and clinical medicine, the localization of a certain functional brain area is often involved, and then surgical treatment or physical device intervention is performed on the specific brain area. For example, the magnetic field intervention of Transcranial Magnetic Stimulation (TMS) equipment on the dorsolateral prefrontal cortex (DLPFC) of the brain must have an accurate positioning of the dorsolateral prefrontal cortex of the patient's head in advance, so that Only in this way can the effectiveness of stimulation be guaranteed, and at the same time, unnecessary damage to other functional brain regions around it can be avoided. At present, th...

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Problems solved by technology

Among the above two methods, the former uses a relatively rough way to individualize the region of interest, while the latter does not consider individualization at all, and directly selects a general template instead of an individual subject. The two methods of the prior art None of the methods can truly achieve individualized and accurate positioning, thereby reducing the clinical value of the later treatment effect, and at the same time, it is impossible to quantitatively evaluate the actual curative effect

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