Super-molecule complex containing amino acid and water-solubility pillar [5] arene and preparation method for complex

A water-soluble, amino acid technology, applied in the preparation of organic compounds, cyanide reaction preparation, medical preparations of non-active ingredients, etc., can solve the problems of inclusion coordination that have not been reported, to increase water solubility, improve Stability, toxicity reduction effect
CN102911071AInactive Publication Date: 2013-02-06SHANGHAI UNIV
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
SHANGHAI UNIV
Publication Date
2013-02-06
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to a super-molecule complex containing amino acid and water-solubility pillar [5] arene and a preparation method for the complex. The complex is a [2] pseudorotaxane type complex in an interpenetrating structure by taking the water-solubility pillar [5] arene as a main body and the basic amino acid as a guest through bonding, wherein the molar ratio of the basic amino acid and the water-solubility pillar [5] arene is 1:1, and the structure of the complex containing water-solubility pillar arene and L-arginine is shown in the description. The complex is formed by inclusion, so that the stability of drug molecules can be improved, the drug can be released directionally, the water solubility is improved, the toxicity is lowered, etc. In addition, the complex can be used for improving the stability of unstable and easily-volatile matters such as cosmetics and fragrances, and the water solubility of the complex is also improved.
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Description

technical field

[0001] The invention relates to a functional supramolecular complex and a preparation method thereof. In particular, a supramolecular complex of amino acid and water-soluble column [5] arene and its preparation method. Background technique

[0002] The concept of molecular recognition was originally proposed by organic chemists and biochemists to study chemical problems in molecular research biological systems. Molecular recognition produces catalysis through transformation and translocation processes. In biological systems, it is the source of information for understanding enzymatic reactions, information transfer, and energy transfer phenomena between species in different media. In the field of analytical chemistry, it constitutes the basis for separation, detection and quantitative determination. Base. The formation of supramolecular inclusions is based on molecular recognition.

[0003] The synthesis and decomposition of molecules in organisms, the tra...

Claims

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