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Adhesive patches and adhesive preparations

A technology of pasting sheets and adhesives, which is applied in viscous dressings, dressings, etc., can solve the problem that the thickness of the end of the adhesive layer is difficult to maintain, and achieve the effects of suppressing cold flow, suppressing exudation and highlighting

Active Publication Date: 2015-12-16
NITTO DENKO CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In fact, the thickness of the end portion of the adhesive layer of the adhesive patch in this example is formed to be thinner than the thickness of the central portion, and it can be inferred that the thickness of the end portion of the adhesive layer is difficult to maintain

Method used

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  • Adhesive patches and adhesive preparations
  • Adhesive patches and adhesive preparations
  • Adhesive patches and adhesive preparations

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1、2 and comparative example 1～3

[0120] Embodiment 1, 2 and comparative example 1~3 adhesive preparation

[0121] (1) Manufacture of adhesive sheets

[0122] Manufacture of a composition for forming an adhesive layer

[0123] For high molecular weight polyisobutylene (viscosity average molecular weight: 4000000, 0.620kg), alicyclic saturated hydrocarbon resin (softening point measured by ring and ball method: 120℃~160℃, 1.127kg), toluene (4.456kg) and n-hexane (4.726 kg) were weighed and stirred in the blending tank for over 24 hours. Medium molecular weight polyisobutylene (viscosity average molecular weight: 55000, 1.071 kg) was weighed, put into a blending tank and the mixture was stirred for more than 24 hours. Thereafter, isopropyl myristate (1.232 kg) and toluene (0.270 kg) were weighed, put into a blending tank, and the mixture was stirred for 4 hours or more to obtain a composition for forming an adhesive layer.

[0124] Manufacture of raw sheets for die cutting

[0125] Using a coating machine co...

experiment example 1

[0130] Experimental example 1 Evaluation of the shape of the adhesive patch

[0131] The various adhesive slides of Examples and Comparative Examples were stained with an aqueous ruthenium acid solution and cut with a cryostat (LR-85 manufactured by YAMATOKOHKI INDUSTRIAL CO., LTD.). The cross section was photographed using FE-SEM (S-4800 manufactured by Hitachi, Ltd.) at 50-power to 1000-power. In the electron micrographs of various adhesive sheets, the scale scales of the peripheral part and the central part were read, thereby measuring the thickness of the PET film and PET non-woven fabric, and the thickness of the main part of the adhesive sheet (the sum of the thickness of the adhesive layer and the thickness of the support). In this case, there are depressions and protrusions on the surface of the PET nonwoven fabric. In the cross-sectional image, 10 protrusions were randomly selected, and the average value of the thickness of the PET non-woven fabric at the protrusion...

experiment example 2

[0137] Experimental Example 2 Evaluation of the performance of taking the adhesive patch out of the package

[0138] Such as Figure 11 Open the sides of the adhesive patch package with scissors or along the V-notch as shown in . While holding the corners of the adhesive patch, it was taken out, and the performance of taking the adhesive patch out of the package was evaluated according to the following three-level evaluation criteria.

[0139] evaluation standard

[0140] ○: Adhesive layer components do not ooze or protrude; can be easily removed

[0141] △: Components of the adhesive layer bleed out or protrude in a part of the adhesive patch; removable

[0142] ×: The components of the adhesive layer ooze out or protrude remarkably; it is difficult to take it out

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Abstract

The invention relates to a glue paster and a glue preparation. The glue paster comprises a support body, a glue layer on at least one surface of the support and a stripping lining pad which is on the opposite surface of the support body to the glue layer, wherein : (a), side face end parts of the glue layer are exposed, (b), at least one side face end part of the glue layer is positioned from a side face end part of the support body to the center part side of the flue paster, and (c), when the face of the stripping lining pad faces downward and is arranged levelly, the distance A between an upper end, in the position of the side face end part of the glue paster, of the support body and the lower end of the stripping lining pad is larger than the thickness B of the center part of the glue paster. The glue paster and the glue preparation can ensure enough skin adhesive force, high resistance can be achieved when the glue paster and the glue preparation is separated from the surface of the skin, and the stripping lining pad is easy to separate.

Description

technical field [0001] The present invention relates to an adhesive patch comprising a support and an adhesive layer formed on at least one surface of the support and an adhesive preparation. Background technique [0002] In recent years, various adhesive patches and adhesive formulations have been developed. Adhesive patches and adhesive formulations are excellent in protecting wound surfaces, continuous transdermal administration of drugs, drug metabolism by hepatic first-pass effect, and avoidance of various side effects. [0003] In general, adhesive patches and adhesive preparations have a support made of woven fabric, nonwoven fabric, plastic film, etc. and an adhesive layer laminated on the support, and the adhesive patch and Adhesive formulations typically have a release liner laminated to the adhesive layer. They are provided in packages made of packaging materials such as resin films and the like. [0004] In such adhesive patches and adhesive preparations, the ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61F13/02
Inventor 播摩润今野昌克桥野亮沼田晃
Owner NITTO DENKO CORP