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Skin-caring composition and preparation method and applications thereof

A skin care and composition technology, applied in the field of skin care composition and its preparation, can solve the problems of little effect and irreversible aging, and achieve the effect of removing skin wrinkles, increasing skin elasticity and luster, and removing scars

Active Publication Date: 2013-04-03
广州美中生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Aging cannot be reversed, but it can be delayed
For many years, people have been looking forward to and doing everything possible to find a panacea that can delay aging, but so far with little success

Method used

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  • Skin-caring composition and preparation method and applications thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Raw materials: in 1000ml, it contains: 1mg of cell growth factor (epidermal growth factor (EGF)), 3.5g of white fungus and appropriate amount of double distilled water.

[0026] Preparation:

[0027] (1) Add the dried white fungus to 1000ml of pure water with a pH of 10 in proportion, cook at 100°C for 3 hours, filter through a mesh screen, take the crude filtrate to adjust the pH to 6.8, microfilter it with a 0.4μm hollow fiber membrane, and take the clarified micro Filtrate; the microfiltrate is ultrafiltered with a hollow fiber membrane with a molecular weight cut-off of 250kd, the first ultrafiltrate is taken, and the first ultrafiltrate is ultrafiltered with a hollow fiber membrane of 8kd, and washed repeatedly with pure water until After the conductivity is 0.1mS / cm, continue to concentrate until the tremella polysaccharide concentration is 1g / 1000ml;

[0028] (2) The alkali-soluble tremella polysaccharide ultrafiltrate was subjected to 121°C, 1.1kg / cm 2 After h...

Embodiment 2

[0031] Raw materials: 1000ml contains: cell growth factor 100mg (of which; epidermal growth factor (EGF) 50mg, fibroblast growth factor (FGF) 25mg, keratinocyte growth factor (KGF) 25mg), white fungus 0.035g, paraben Esters 0.1g, and appropriate amount of double distilled water.

[0032] Preparation:

[0033] (1) Add dried Tremella in proportion to 1000ml of pure water with a pH of 12, cook at a high temperature of 140°C for 1 hour, filter through a mesh sieve, take the crude filtrate to adjust the pH to 7, microfilter it with a 0.45μm hollow fiber membrane, and take the clarified Microfiltrate; the microfiltrate is ultrafiltered with a hollow fiber membrane with a molecular weight cut-off of 350kd, and the first ultrafiltrate is taken, and the first ultrafiltrate is ultrafiltered with a hollow fiber membrane of 12kd, and washed repeatedly with pure water After the conductivity is 0.1mS / cm, continue to concentrate until the concentration of tremella polysaccharide is 0.01g / 10...

Embodiment 3

[0038] Raw materials: 1000ml contains: cell growth factor 2mg (of which; epidermal growth factor (EGF) 1mg, fibroblast growth factor (FGF) 0.5mg, keratinocyte growth factor (KGF) 0.5mg), white fungus 2.8g, Nepal Gold propyl ester 2mg, butylparaben 8mg, and appropriate amount of double distilled water.

[0039] (1) Add dried tremella in proportion to 1000ml of pure water with a pH of 10, cook at 100°C for 1 hour, filter through a mesh screen, take the crude filtrate to adjust the pH to 6.8, microfilter it with a 0.4μm hollow fiber membrane, and take the clarified Microfiltrate; the microfiltrate is ultrafiltered with a hollow fiber membrane with a molecular weight cut-off of 250kd, the first ultrafiltrate is taken, and the first ultrafiltrate is ultrafiltered with a hollow fiber membrane of 8kd, and washed repeatedly with pure water After the conductivity is 0-1mS / cm, continue to concentrate until the tremella polysaccharide concentration is 0.8mg / ml;

[0040] (2) Mix the alka...

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Abstract

The invention discloses a skin-caring composition and a preparation method and applications thereof. The skin-caring composition comprises 0.01-1 mg / ml tremella polysaccharide, 1-100 microgram / ml cell growth factors and a solvent for preparing each raw material solution with predetermined content. According to the skin-caring composition and the preparation method and applications thereof, the tremella polysaccharide and the cell growth factors are synergistically made into the skin-caring composition and preparation, the tremella polysaccharide and the cell growth factors are mutually complemented in function, the using effects of the two matters are larger than the sum of individual using effects due to the synergistic effect, so that unexpected effect is obtained in skin maintenance. The skin-caring composition provided by the invention not only can be used for daily skin maintenance, such as removing skin wrinkles, increasing skin elasticity and sheen, but also can be used for sensitive skin maintenance; and simultaneously, the skin-caring composition also can be used for recovering wound, removing scars and beautifying skin after the wound is healed or minimally invasive cosmetic surgery is performed.

Description

technical field [0001] The invention relates to the field of skin care, in particular to a skin care composition and its preparation method and application. Background technique [0002] Human aging, including skin aging, is an irreversible natural phenomenon. Due to the influence of factors such as intense life and work rhythm, environmental pollution and unhealthy living habits, this phenomenon of aging (firstly manifested as skin aging) often occurs early. The specific manifestations are so-called sub-healthy skin such as wrinkles, uneven skin tone, roughness, lack of elasticity, dark and yellowish complexion, spots and freckles, dryness, and enlarged pores. In 1997, a survey report by the World Health Organization (WHO) showed that among the yellow race, less than 10% of the facial skin was in a healthy state, more than 20% were in a sick state, and 70% were in a sub-healthy state. . [0003] From a biomedical point of view, "sub-healthy skin" is a kind of skin qualit...

Claims

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Application Information

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IPC IPC(8): A61K8/73A61K8/64A61Q19/00A61P17/02
Inventor 涂桂洪邓惠平
Owner 广州美中生物科技有限公司
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