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Double-vitamin calcium carbonate composition

A calcium carbonate composition and a technology for the composition, applied in the field of medicine, can solve the problems of large side effects of calcium supplementation products, insignificant calcium supplementation effect, poor calcium supplementation effect, etc., so as to reduce fracture risk, avoid eye inflammation, and prevent falls. Effect

Inactive Publication Date: 2013-04-03
KUNMING BANGYU PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are many calcium supplement products, some of which are too complex and involve the supplement of various nutrients, and the calcium supplement effect is not obvious; Poor; some calcium supplement products still have problems such as large side effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Embodiment one: the preparation of granule

[0022] Weigh calcium carbonate 750g, vitamin K 1 2g, Vitamin K 3 2g, Vitamin K 4 2g, Vitamin D 2 3mg, Vitamin D 3 2mg and 2244g of sucrose, then dissolve vitamin K with 40ml of 95% ethanol 1 , Vitamin K 3 , Vitamin K 4 , Vitamin D 2 , Vitamin D 3 , then dilute with 350ml of purified water to obtain a wetting agent for later use. After the calcium carbonate and sucrose are uniformly mixed, the obtained wetting agent is used to make a soft material, granulated, dried at 50° C., sized, and packaged separately to obtain the granules.

Embodiment 2

[0023] Embodiment two: the preparation of granule

[0024] Weigh calcium carbonate 1500g, vitamin K 1 12g, Vitamin D 2 5mg and 1488g of sucrose, then dissolve vitamin K with 30ml of 95% ethanol 1 , Vitamin D 2 , then dilute with 250ml of purified water to obtain a wetting agent for later use. Mix calcium carbonate and sucrose evenly, use the obtained wetting agent to make soft materials, granulate, dry at 40°C, size the granules, and pack separately to obtain the granules.

Embodiment 3

[0025] Embodiment three: the preparation of tablet

[0026] Weigh calcium carbonate 750g, vitamin K 2 12g, Vitamin D 3 5mg, microcrystalline cellulose 100g and sodium starch glycolate 20g, then dissolve vitamin K with 35ml of 95% ethanol 2 , Vitamin D 3 , then dilute with 200ml of purified water to obtain a wetting agent for later use. Mix calcium carbonate, microcrystalline cellulose and sodium starch glycolate evenly, use the obtained wetting agent to make a soft material, granulate, dry at 50°C, granulate, add 2.5g of magnesium stearate and mix evenly. Tablet, promptly get described common tablet.

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Abstract

The invention relates to a double-vitamin calcium carbonate composition belonging to the technical field of medicine. The composition comprises the following active components: 300-3500 parts by weight of calcium carbonate, 0.1-60 parts by weight of vitamin K and 0.001-0.1 part by weight of vitamin D. According to the invention, because of the scientific formula, calcium can be effectively supplemented; and the double-vitamin calcium carbonate composition is safe and convenient to take.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a two-dimensional calcium carbonate composition. Background technique [0002] Calcium is the most abundant inorganic salt in the human body. The content of calcium in a normal human body accounts for about 0.5%-2.0% of the body weight, of which 99% of calcium exists in bones and teeth, and 1% of calcium is mostly in the form of ions The state exists in soft tissue, extracellular fluid and blood, and maintains a dynamic balance with bones. Calcium has the functions of maintaining the normal response of nerves and muscles, regulating heart beat, keeping the heart contracting and relaxing continuously and alternately, maintaining muscle contraction and transmission of nerve activity and other activities. Due to the problems of eating habits, the residents of our country generally need to take appropriate calcium supplements in order to better protect the health of residents. Now...

Claims

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Application Information

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IPC IPC(8): A61K33/10A61P3/14A61P19/10A61P19/08A61K31/59A61K31/05
Inventor 王冰张永胜刘晓凯郑光明
Owner KUNMING BANGYU PHARMA
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