Compound fluconazole gel for pets and preparation process thereof
A technology of compound fluconazole gel and fluconazole, which is applied in the field of compound fluconazole gel for pets and its preparation, can solve the problems of low irritation, high safety, good air permeability, etc., and achieve good absorption and uniformity Good, breathable effect
Inactive Publication Date: 2013-05-08
QINGDAO VLAND BIOTECH INC
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Problems solved by technology
[0002] At present, pet skin diseases are extremely difficult to treat, and mixed infections are serious. The existing medicines for treating pet skin diseases mostly use human medicines. Because the skin of humans and animals is very different, it is difficult for the medicines to play their due role, and human medicines for veterinary It is in violation of my country's veterinary drug regulations, so there is an urgent need for pet-specific drug formulations for skin treatment in pet clinics
[0003] The gel has good air permeability and is especially suitable for the underdeveloped sweat glands of pet skin, which is conducive to the self-recovery of the skin. The gel uses less organic solvents, is less irritating, and has high safety. Even if the pet licks it, it will be fine. Therefore, the gel is more suitable for the clinical use of pets. At present, there is no gel formulation for the treatment of pet-related skin diseases at home and abroad.
Method used
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Experimental program
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Embodiment Construction
[0010] Take 2g of Carbomer 940, add 0.05g of ethylparaben to 20mL of water to swell overnight. The next day, take 1.5g of fluconazole, 3g of lincomycin hydrochloride, 1.5g of borneol, 0.5g of indomethacin, and 1g of lidocaine, add water and grind them, add them to carbomer respectively, and stir to make the mixture uniform without a large amount of bubble. Add 10mL triethanolamine, 0.5mL azone. Continue to stir until fully combined. Obtain compound fluconazole gel.
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Abstract
The invention belongs to the technological field of veterinary medicines. Specifically, the invention mainly relates to a prescription of a compound fluconazole gel treating mixed infection of bacteria, fungi and mites in pets and a preparation process thereof. The invention provides an externally applied gel preparation with good breathability and transdermal absorption, small irritation as well as good curative effects, i.e. the compound fluconazole gel. The compound fluconazole gel prepared according to the prescription and process provided in the invention overcomes the disadvantages of high oil content and poor breathability in existing veterinary compound fluconazole ointments, fills the blank of the veterinary drug market, and has the characteristics of good curative effects and good breathability.
Description
technical field [0001] The invention discloses a compound fluconazole gel for pets and a preparation process thereof, belonging to the technical field of veterinary drug preparations. Background technique [0002] At present, pet skin diseases are extremely difficult to treat, and mixed infections are serious. The existing medicines for treating pet skin diseases mostly use human medicines. Because the skin of humans and animals is very different, it is difficult for the medicines to play their due role, and human medicines for veterinary It is in violation of my country's veterinary drug laws and regulations, so there is an urgent need for pet-specific drug formulations for skin treatment in pet clinics. [0003] The gel has good air permeability and is especially suitable for the underdeveloped sweat glands of pet skin, which is conducive to the self-recovery of the skin. The gel uses less organic solvents, is less irritating, and has high safety. Even if the pet licks it, ...
Claims
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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7056A61K31/4196A61K31/405A61K31/167A61K31/045A61K9/00A61P17/00
Inventor 刘元元郝智慧王艳玲
Owner QINGDAO VLAND BIOTECH INC
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