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Skin external composition containing tangeretin and egcg

A technology of epigallocatechin and external composition, which is applied in the field of external skin composition, can solve problems such as use restrictions, and achieve excellent skin whitening effect

Active Publication Date: 2013-07-31
AMOREPACIFIC CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] In order to meet people's needs, ascorbic acid, kojic acid, arbutin, hydroquinone, glutathione or their derivatives or substances with tyrosinase inhibitory activity have been combined with cosmetics or pharmaceuticals in the past. However, due to their whitening effect, safety issues on the skin, dosage forms and stability when cosmetics are used, the use is limited.

Method used

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  • Skin external composition containing tangeretin and egcg
  • Skin external composition containing tangeretin and egcg
  • Skin external composition containing tangeretin and egcg

Examples

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Embodiment

[0048] Hereinafter, the configuration and effects of the present invention will be further specifically described based on experimental examples and formulation examples. However, these experimental examples and formulation examples are only illustrative purposes for helping the understanding of the present invention, and the scope and range of the present invention are not limited by the following examples.

reference example 1

[0049] Reference Example 1: Manufacture of Citrus Peel Extract Containing Orange Peel Crystals

[0050] The citrus peels were washed with purified water and dried. The citrus peel that has been dehydrated is crushed, and the active ingredient is extracted by cold soaking extraction at room temperature for 40-48 hours. After the extract was filtered once with a 250 μm sieve, it was centrifuged to obtain the supernatant. The resulting liquid was then filtered through filter papers with 3 μm, 1 μm, and 0.5 μm sieves. Add 10% of 1,3-butanediol (Butylene glycol), 0.5% of phenoxyethanol, and 0.05% of ethylhexylglycerin (Ethylhexylglycerin), and filter again with 0.2-0.3 μm filter paper to obtain citrus peel extract.

reference example 2

[0051] Reference Example 2: Production of EGCG-containing green tea extract

[0052] After the green tea leaves are washed with purified water, they are dried. The green tea leaves that have been dehydrated are pulverized, and the active ingredients are extracted by cold soaking extraction at room temperature for 40-48 hours. After the extract was filtered once with a 250 μm sieve, it was centrifuged to obtain the supernatant. The resulting liquid was then filtered through filter papers with 3 μm, 1 μm, and 0.5 μm sieves. Add 10% 1,3-butanediol, 0.5% phenoxyethanol, and 0.05% ethylhexylglycerin, and filter again with 0.2-0.3 μm filter paper to obtain green tea extract.

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Abstract

The invention relates to a skin external composition containing tangeretin and EGCG. Moreover, the invention provides a skin external composition using orange peel extract containing tangeretin and green tee extract containing EGCG, which does not stimulate skin and has skin whitenning effect with saftey.

Description

technical field [0001] The present invention relates to a composition for external use on skin which contains orange peel crystals and epigallocatechin (EGCG) and has whitening effect. Background technique [0002] Human skin color is determined by many factors, including the activity of melanocytes (melanocytes), the distribution of blood vessels, skin thickness, and the presence or absence of pigments in and out of the human body such as carotenoids and bilirubin. important role. [0003] Among them, the most important factor is black pigment called melanin produced by the action of various enzymes such as melanocyte tyrosinase in the human body. Physiological factors associated with genetic factors, hormone secretion, stress, etc., and environmental factors such as ultraviolet radiation affect this melanin. [0004] The melanin produced in the melanocytes of the body skin is a phenolic macromolecular substance in the form of a complex of melanin and protein, which block...

Claims

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Application Information

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IPC IPC(8): A61K8/49A61K8/97A61K31/353A61K36/82A61Q19/02A61P17/00A61K31/325
CPCE03C1/0412F16K11/07F16K31/602Y10S303/10
Inventor 刘世真金恩惠白锡润
Owner AMOREPACIFIC CORP
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