Novel slow-release breast perfusion agent for preventing cow subclinical mastitis and preparation method thereof

The technology of subclinical mastitis and perfusion agent is applied in the field of slow-release breast perfusion agent for preventing subclinical mastitis in dairy cows and its preparation field, which can solve the problems of hidden danger of food safety, economic loss, increase of white blood cell content and the like, and achieves reduction of drug administration frequency, good stability, and the effect of preventing recessive mastitis in dairy cows
CN103230366AActive Publication Date: 2013-08-07中国牧工商集团有限公司 +1
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
中国牧工商集团有限公司
Publication Date
2013-08-07

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Abstract

The invention provides a novel slow-release breast perfusion agent for preventing cow subclinical mastitis and a preparation method thereof. 100g of the novel slow-release breast perfusion agent comprises 1 to 5g of cephapirin benzathine, 0.5 to 8g of polyethylene glycol-400, Tween materials or propylene glycol, 0.5 to 8g of fatty alcohol-polyoxyethylene ether, cyclomethylene glyceryl ether, glyceryl triacetate or poloxamer, 0.02 to 0.05g of vitamin E, 0.05 to 0.1g of benzyl alcohol, and the balance soybean oil for injection, liquid paraffin or median-chain triglyceride. The invention also provides a preparation method of the novel slow-release breast perfusion agent. The novel slow-release breast perfusion agent is suspended colloid, can be released slowly, has low administration frequency, can prevent cow subclinical mastitis in a mild shortage stage, and does not produce residues in milk in a lactation stage. Compared with foreign like products, the suspended colloid has better stability.
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Description

technical field

[0001] The invention relates to the field of veterinary drug preparation, in particular to a slow-release udder perfusion agent for preventing latent mastitis in cows and a preparation method thereof. Background technique

[0002] Dairy cow mastitis is one of the diseases that cause the most serious economic loss in dairy farms, especially dairy cow recessive mastitis, which is still one of the important diseases that endanger the dairy industry in the world because it has no obvious clinical symptoms and is easy to be ignored. Due to changes in the physical and chemical properties of the milk secreted by sick cows with mastitis, increased white blood cell content, and pathological changes in mammary gland tissue, it not only causes serious economic losses to the dairy farming and dairy processing industries, but also brings certain risks to food safety. hidden dangers.

[0003] Sustained-release preparations mean that by delaying the release rate of the dru...

Claims

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