Preparation method of powder of medicine for treating postnatal perineum mucosal lesion

A mucous membrane and drug technology, applied in the field of powder preparation of drugs for treating postpartum perineal mucosal lesions, can solve problems such as unfavorable long-term prognosis, irritation of mucous membranes, mucosal irritation, etc. Effect

Inactive Publication Date: 2015-03-18
丁霄雁 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But in fact, the basic pathology of the disease is as follows: postpartum estrogen levels drop rapidly, causing relatively atrophy of the vaginal wall, thinning of the mucous membrane, reduction of glycogen content in epithelial cells, increase of Ph value in the vagina, decrease of local resistance, pathogenic bacteria Easy to invade and reproduce and cause inflammation
The magnesium sulfate and potassium permanganate flushing solution is also a kind of stimulation to the mucous membrane, which can solve the problem of early mucous membrane edema, but it is not good for the long-term prognosis.
[0004] There are many traditional Chinese medicine perineal wet dressings, but most of them are aimed at women of childbearing age. The prescriptions often contain dehumidification drugs such as Sophora flavescens, Cnidium, Kochia, and Smilax. Mucous membrane thinning, external application of the above bitter cold and dampness medicine will irritate the mucous membrane even more, leading to aggravation of the condition
And the bitter cold of the above-mentioned drugs is not conducive to postpartum recovery

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Example 1, the weight ratio of raw materials: Pittogonia bark 20g, triangle grass 10g, bobbin 6g, mountain ginger 10g, mulberry 6g, cat's claw grass 10g, burnt malt 10g, burnt Shenqu 10g, ephedra root 10g, saponins Thorn 2g, peach gum 6g, calamus 20g.

[0040] The preparation method of Example 1 is: mix Pittogonia bark, trigonum chinensis, bobbin, mountain ginger, mulberry, cat's claw, burnt malt, burnt Shenqu, ephedra root, saponin thorn, peach gum, and iris calamus, and add water Decoct, take the filtrate after 30 minutes, add water to the dregs of the medicine and continue to decoct for 20 minutes, then take the filtrate, and wash the filtrate twice, once a day.

Embodiment 2

[0041] Example 2, the weight ratio of raw materials: 10 parts of Pittogonia bark, 6 parts of triangular grass, 3 parts of bobbin, 6 parts of mountain ginger, 3 parts of mulberry, 6 parts of cat's claw, 6 parts of Jiaomaiya, 6 parts of Jiao Shenqu 3 parts, 6 parts of ephedra root, 1 part of saponins, 3 parts of peach gum, and 10 parts of calamus calamus.

Embodiment 3

[0042] Example 3, the weight ratio of raw materials: 20 parts of Pittogonia bark, 10 parts of triangular grass, 6 parts of bobbin, 10 parts of mountain ginger, 6 parts of mulberry, 10 parts of cat's claw grass, 10 parts of burnt malt, 10 parts of Jiao Shenqu 10 parts, 10 parts of ephedra root, 2 parts of saponins, 6 parts of peach gum, 20 parts of iris calamus.

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PUM

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Abstract

The invention discloses a preparation method of powder of a medicine for treating postnatal perineum mucosal lesion, which is used for solving the problems in treatment by use of a medicine for treating postnatal perineum mucosal lesion. The preparation method is characterized by comprising the following steps of: (1) performing reduced-pressure distillation on the coarse powder of cortex erythrinae, radix ranunculi ternati and radix ephedrae, and extracting volatile oil; (2) performing reduced-pressure decoction on gastrodia elata to obtain filtrate; (3) decocting trikeraia hookeri, alpinia japonica, herba taxilli, coking malt, coking medicated leaven, spina gleditsiae, peach gum and rhizoma anemones altaicae and the dregs obtained in the step (1) with water to obtain filtrate for later use; (4) combining the filtrates obtained by the steps (2) and (3), performing reduced-pressure concentration to obtain a dry extract, and grinding the dry extract to obtain dry extract powder; and (5) spraying the volatile oil obtained in the step (1) into the dry extract powder obtained in the step (4), mixing uniformly, screening by a 100-mesh sieve, and sub-packing to obtain the powder. Clinical experiments prove that the medicine for treating postnatal perineum mucosal lesion has the characteristics of good curative effect and high safety, and deserves clinical application and popularization.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a method for preparing a powder for treating postpartum perineal mucosal lesions. Background technique [0002] The postpartum uterus, cervix, vagina, and perineum will undergo a series of changes due to the rapid decline in hormone levels. For the perineum, during childbirth, the fetus squeezes the outer opening of the vagina. It often causes perineal congestion, edema, or varying degrees of laceration, which gradually disappear within 7 days thereafter. At the same time, the surrounding folds of the perineum will be reduced, the mucosa in the vagina will be flat, and the defense of the mucosa will be reduced, which will easily lead to symptoms such as vulvar itching and vaginal dryness. Generally speaking, in a short period of time, the vaginal mucosa is not easy to fully recover to the situation before pregnancy. Only after the cessation of breastfeeding, menstru...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9062A61K9/14A61P15/00
Inventor 丁霄雁姜春杰
Owner 丁霄雁
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