Chinese medicinal composition

A technology of composition and traditional Chinese medicine, applied in the field of traditional Chinese medicine composition

Inactive Publication Date: 2013-10-23
石强
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, with the advent and popularization of chemotherapy drugs such as 5-fluorouracil, taxanes, hydroxycamptothecin, irinotecan, Xeloda, etc., the incidence of chemotherapy-related diarrhea has increased year by year. Treatment can easily lead to dehydration, malnutrition, serum electrolyte disorder, acid-base balance disorder, etc., which not only bring great disadvantages to the recovery of the body, but also bring certain difficulties to periodic chemotherapy. Effective treatment has become an important part of the overall treatment of cancer patients
[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, and at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

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  • Chinese medicinal composition

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Experimental program
Comparison scheme
Effect test

Embodiment approach

[0031] The first step: preparation of various extracts

[0032] (1) Preparation of the concentrated extract of radish and gallnut decoction

[0033] According to the compatibility ratio of 1-5:1, take radish seeds and gallnuts, soak them in distilled water, heat and decoct, filter, add distilled water to the medicinal residues, soak, decoct, and filter in the same way, mix the two filtrates, heat and concentrate, and super Membrane filtration, drying under reduced pressure, that is.

[0034] (2) Preparation of Raphanusin

[0035] Grind radish seeds, add excess n-hexane to degrease, enzymatically hydrolyze with pH 7.0 phosphate buffer, add dichloromethane to extract 3 times, combine solvents, remove organic solvent under reduced pressure, and dissolve the residue with 10% ethanol solution by volume fraction , extracted three times with n-hexane to remove grease, then extracted the ethanol phase three times with dichloromethane, combined the solvents, and removed the dichlorom...

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Abstract

The invention relates to a Chinese medicinal composition, which consists of a semen raphani gallnut decocted concentrated extract, raphanin and a gallnut acetone extract in a ratio of 2-6:3-7:1-7. The composition has excellent efficacy on cancer chemotherapy related diarrhea and can have a synergistic effect on cancer chemotherapy at the same time.

Description

Technical field [0001] The present invention involves a Chinese medicine composition, and more specifically involves a traditional Chinese medicine composition composed of Laizunzi Wulin Water Decoction, Laosonin and Wulopolitone extract.Things are used in the use of drug -related diarrhea related to cancer chemotherapy and the effectiveness of cancer treatment. Background technique [0002] Malignant tumors are one of the main diseases that endanger human survival and health. The treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine. The effect of chemotherapy treatment of tumors is particularly prominent.The single or combined use of chemotherapy drugs will cause patients with diarrhea and other toxic and side effects. After tumor chemotherapy, diarrhea is also called chemotherapy -related diarrhea.In recent years, with the appearance and promotion of chemotherapy drugs such as 5-fluoridine, pacane, hydroxyl cither alkali, Ilidekang, Hi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/31A61P1/12A61P35/00A61K35/64A61K31/26
Inventor 石强
Owner 石强
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