Compound mixture with antihyperlipidemic effect and preparation method thereof

Abstract

The invention relates to a compound mixture and aims at providing a compound mixture which has an antihyperlipidemic effect and a significant clinical effect, is prepared from pure Chinese herb medicines and is non-irritant to a human body. The compound mixture is prepared from 100 parts by weight of hawthorn, 80 parts by weight of fructus chebulae and 80 parts by weight of fructus piperis longi. A preparation method of the compound mixture sequentially comprises the following steps of: a, weighing Chinese herbal medicine raw materials in dosage; b, drying the Chinese herbal medicine raw materials, grinding the Chinese herbal medicine raw materials into fine powder, and sieving for spare use; c, adding 1560ml of distilled water into the fine powder obtained by the step b, soaking to be clear, decocting for 30 minutes, filtering, then adding 1560ml of distilled water and decocting for 15 minutes, filtering, merging filtrate, concentrating a solvent, and drying into fine powder; and d, adding a pharmaceutically acceptable carrier and / or excipient into the fine powder obtained by the step c, and preparing capsules by adopting the traditional preparation process. The compound mixture is prepared by adopting non-toxic traditional Chinese medicines as main raw materials, is non-toxic and non-irritant and effective in treatment and produces small side effect.

Description

technical field [0001] The invention relates to a compound mixture with blood lipid-lowering effect and a preparation method thereof. Background technique [0002] In the 21st century, people's living standards have been significantly improved, and at the same time some lifestyle-related diseases have become the primary cause of threats to human health. The mortality rate of cardiovascular and cerebrovascular diseases in our country has risen to the second place. Hyperlipidemia, that is, the increase of serum total cholesterol, triglyceride, and low-density lipoprotein is a major cause of cardiovascular and cerebrovascular diseases. A large number of epidemiological surveys and studies have shown that hyperlipidemia is an important risk factor for many diseases such as atherosclerosis (AS), coronary heart disease (CHD), hypertension, diabetes, and cholelithiasis, which seriously endangers human health. . [0003] At present, these Chinese patent medicines for the treatmen...

AI Technical Summary

Problems solved by technology

[0003] At present, these Chinese patent medicines for the treatment of hyperlipidemia have common adverse reactions such as headache, insomnia, transient changes in bowel habits, and nausea. These adverse reactions mostly occur during long-term use, and are generally rare in short-term use

What needs special attention is that if this type of drug is used in combination with the lipid-lowering drug gemfibrozil, more serious problems will often occur. In mild cases, it can lead to liver and kidney function damage, muscle pain, and in severe cases, rhabdomyolysis and renal failure may occur. etc., can even lead to death or permanent disability

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