Oral composition and method of forming and using same

An oral composition and the technology of the composition are applied in the directions of drug combination, drug delivery, and pharmaceutical formulation, and can solve the problems of poor taste and the like

Inactive Publication Date: 2013-10-30
DR FRESH INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, other formulations used to treat dry mouth are reported to be less mouth-feeling

Method used

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  • Oral composition and method of forming and using same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] A translucent oral composition comprising the following ingredients was prepared by premixing propylene glycol and carboxymethylcellulose; adding xylitol, sorbitol, aloe vera gel, zinc gluconate, and poloxamer 407 to purified water and mix until the poloxamer 407 is completely dissolved; add the propylene glycol / carboxymethyl cellulose mixture to the xylitol mixture; slowly add benzoic acid and sodium phosphate to the mixture and mix About 15 minutes or more; measure pH; add phytic acid and lactoferrin to said mix and mix for about 15 minutes; add lysozyme, glucose oxidase, peptidase, amylase, papain, and amylog Glucosidase was added to the mix and mixed for about 15 minutes; and natural flavor was added to the mix and mixed for about 30 minutes.

[0036] The oral composition has a pH between about 5 and about 5.5 and a specific gravity of about 1.01 to about 1.04.

[0037]

Embodiment 2

[0039] The composition of Example 1 is used to treat dry mouth in patients with chronic kidney disease. The patient is instructed to apply the composition of Example 1 to the oral cavity, rinse the mouth thoroughly for about 30 seconds to about 1 minute, and then spit out (expel) the composition, repeating the application 2-3 times a day. Patients are also instructed not to rinse the mouth immediately after administering the composition or to eat immediately after administering the composition. The method of Example 2 reduces the symptoms of dry mouth, which in turn is believed to reduce or prevent excess fluid, which can lead to heart disease and even death in patients with chronic kidney disease caused by ventricular dystrophy.

Embodiment 3

[0041] The composition of Example 1 was given to diabetic patients suffering from dry mouth which leads to chapped lips and aphtha. The patient is instructed to apply the composition of Example 1 to the oral cavity, rinse well for about 30 seconds to about 1 minute, and then spit out the composition, repeating the application 2-3 times a day. Patients are also instructed not to rinse the mouth or eat immediately. When the composition of Example 1 was used, the patient's dry mouth was relieved and no aphthous sores appeared.

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PUM

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Abstract

An oral composition for the treatment of dry mouth symptoms and other conditions, a method of forming the oral composition, and a method of using the oral composition are disclosed. The oral composition includes a plurality of enzymes to prevent formation of and / or facilitate the break up of biofilm in an oral cavity and a metal ion management system to inhibit growth of gram negative bacteria.

Description

[0001] Cross references to related patent applications [0002] This application claims Provisional Application No. 61 / 385,115, filed September 21, 2010, entitled "Oral Rinse and Methods of Making and Using It"; and Methods of Use," and Provisional Application No. 61 / 413,783, filed November 15, 2010, entitled "Oral Rinse and Methods of Making and Using It." technical field [0003] The present invention broadly relates to compositions and methods for promoting and maintaining oral health. More specifically, the present invention relates to oral compositions and methods for treating or preventing "dry mouth," halitosis, tooth and gum disease, and other conditions. Background technique [0004] Maintaining oral health is often important for a number of reasons. A variety of conditions, from bad breath to general health problems, can occur if oral health is not maintained. Such conditions include, for example, tooth decay, tooth staining, gum disease, tooth loss, and even ge...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K47/36A61K47/38A61K47/30A61K9/08A61K9/20A61P1/02A61P31/00A61P1/00
CPCA61K9/006A61K31/6615A61K38/443A61K38/4886A61K31/198A61K38/47A61K38/40A61K38/4873A61K33/30A61P1/00A61P1/02A61P31/00A61K2300/00
Inventor P·南达
Owner DR FRESH INC
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