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Methyl ester resin-containing vaginal mold

A resin and mold technology, applied in the field of vaginal molds containing methyl ester resin, can solve problems such as reducing the artificial vaginal contracture rate, and achieve the effect of reducing the contracture rate

Inactive Publication Date: 2013-12-11
苏州市马尔泰新材料有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, there is no report on the vaginal mold of methyl ester resin that can greatly reduce the contracture rate of the artificial vagina and release estrogen

Method used

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  • Methyl ester resin-containing vaginal mold
  • Methyl ester resin-containing vaginal mold

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] 1. Drugs and preparations:

[0016] 1. Estrogen: raw material drug of estradiol.

[0017] 2. Methyl methacrylate resin compound.

[0018] Second, equipment

[0019] Pressure forming machine (model: XLB-D400-400), rubber mixing machine (model: JTC-752A), electronic platform scale (model: TSC-6), electric blast drying oven (model: 101A-1B), drying oven ( Model: 101-3), three-roll mill (model: SG-150), weighing display (model: XK3130).

[0020] Three, material preparation

[0021] Weigh 100 g of methyl methacrylate resin compound, and weigh 25 g of estradiol.

[0022] Put the two kinds of raw materials into the rubber mixing machine and mix them, so that the rubber material and the drug can be mixed evenly, and the thinning pass is performed 10 times, so that the drug can be more evenly dispersed in the rubber material.

[0023] Fourth, vaginal mold preparation:

[0024] Weigh 10g of the material, put it into a mold and press it; temperature 140°C, time 12min, pressu...

Embodiment 2

[0026] One, medicine and preparation: Same as Example 1.

[0027] Two, equipment: with embodiment 1.

[0028] 3. Material preparation: Weigh 100 g of methyl methacrylate resin compound, weigh 30 g of estradiol, and the others are the same as in Example 1.

[0029] 4. Vaginal mold preparation: Same as Example 1.

Embodiment 3

[0031] One, medicine and preparation: Same as Example 1.

[0032] Two, equipment: with embodiment 1.

[0033] 3. Material preparation: Weigh 100 g of methyl methacrylate resin compound, weigh 50 g of estradiol, and the others are the same as in Example 1.

[0034] 4. Vaginal mold preparation: Same as Example 1.

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PUM

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Abstract

The invention relates to a methyl ester resin-containing vaginal mold, which consists of a polymethyl methacrylate resin and estradiol, wherein the weight ratio of the polymethyl methacrylate resin to the estradiol is 20:(5-8). The methyl ester resin-containing vaginal mold has the advantages that the vaginal mold contains an estrogen, so that the contracture rate of an artificial vagina is greatly lowered; the vaginal mold with estrogen sustained-releasing capability is prepared by combining the polymethyl methacrylate resin with the estrogen, so that vaginal mold treatment and estrogen treatment are effectively integrated; therefore, the vaginal mold with the sustained-releasing capability has huge potential to clinical application in future.

Description

technical field [0001] The invention relates to a vaginal mold, in particular to a vaginal mold containing methyl ester resin. Background technique [0002] Most patients with congenital absence of vagina have Rokitansky-Kuster-Hauser syndrome (RKH syndrome), which is the result of bilateral paramesonephric duct hypoplasia during the embryonic period, and the karyotype is 46XX. The treatment of patients with congenital absence of vagina has surgical treatment and non-surgical treatment. Surgical treatment includes vulvovaginoplasty (Williams method), acupoint skin grafting method (McIndol method), peritoneal vagina replacement method (Rothman method), sigmoid colon replacement vagina method (Pratl method), amniotic membrane replacement vagina method, and new biomaterial vaginal reconstruction, etc. , The application of the vaginal mold is a very important part of the post-vaginoplasty treatment. A vaginal mold should be placed for 3 months to half a year after the operatio...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/82A61M31/00A61K9/02A61K31/565A61P15/02
Inventor 王强
Owner 苏州市马尔泰新材料有限公司
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