Drug composition for treating red skin disease of grass carp and preparation method of drug composition

A composition and technology for erythroderma, which are applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, antibacterial drugs, etc., can solve problems such as weak bacteriostatic effect of fenugreek, and achieve a simple, easy, and suitable preparation method. The effect of mass production

Active Publication Date: 2013-12-11
泰州市春达动物药业饲料有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The antibacterial concentration of lupulone is between 1:100000

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] A medicinal composition for treating red skin disease of grass carp, comprising the following traditional Chinese medicines, the parts by weight of which are: 10 parts of Humulus japonicus, 20 parts of Dijincao, 2 parts of Neem leaves, 20 parts of Houttuynia cordata, 2 parts of Cypress leaves, Garlic 2 parts.

[0024] The preparation method of the pharmaceutical composition for the treatment of grass carp red skin disease, comprises the following steps:

[0025] 1) Weigh 10 parts of Humulus japonicus plus 10 times 70% ethanol, and use supercritical CO 2 Extract the active ingredients of Humulus japonicus;

[0026] 2) Weigh 20 parts of Dijincao and add 10 times the amount of 75% ethanol to carry out ethanol reflux extraction, extract 5 times, each time for 2.5h to obtain the active ingredients of Dijincao;

[0027] 3) Weigh 2 parts of neem leaves, 2 parts of cypress leaves, 15 parts of Houttuynia cordata, 10 parts of garlic, add 20 times of water and decoct for 2 hours...

Embodiment 2

[0032] A medicinal composition for treating red skin disease of grass carp, comprising the following traditional Chinese medicines in parts by weight: 30 parts of Humulus chinensis, 30 parts of Dijincao, 10 parts of neem leaves, 25 parts of Houttuynia cordata, 10 parts of cypress leaves, Garlic 7 parts.

[0033] The preparation method of the pharmaceutical composition for the treatment of grass carp red skin disease, comprises the following steps:

[0034] 1) Weigh 30 parts of Humulus japonicus plus 15 times 70% ethanol, and use supercritical CO 2 Extract the active ingredients of Humulus japonicus;

[0035] 2) Weigh 30 parts of Dijincao and add 15 times the amount of 75% ethanol to carry out ethanol reflux extraction, extract 5 times, each time for 2.5h to obtain the active ingredients of Dijincao;

[0036] 3) Weigh 10 parts of neem leaves, 10 parts of cypress leaves, 25 parts of Houttuynia cordata, 20 parts of garlic, add 25 times of water and decoct for 2~4 hours, filter ...

Embodiment 3

[0042] A medicinal composition for treating red skin disease of grass carp, comprising the following traditional Chinese medicines in parts by weight: 20 parts of Humulus chinensis, 25 parts of Dijincao, 8 parts of neem leaves, 22 parts of Houttuynia cordata, 7 parts of cypress leaves, Garlic 4 parts.

[0043] The preparation method of the pharmaceutical composition for the treatment of grass carp red skin disease, comprises the following steps:

[0044] 1) Weigh 20 parts of Humulus japonicus plus 12 times 70% ethanol, and use supercritical CO 2 Extract the active ingredients of Humulus japonicus;

[0045] 2) Weigh 25 parts of Dijincao and add 13 times the amount of 75% ethanol to carry out ethanol reflux extraction, extract 5 times, each time for 2.5h to obtain the active ingredients of Dijincao;

[0046] 3) Weigh 8 parts of neem leaves, 7 parts of cypress leaves, 22 parts of Houttuynia cordata, 4 parts of garlic, add 23 times of water and decoct for 3 hours, filter to obta...

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PUM

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Abstract

The invention discloses a drug composition for treating red skin disease of grass carp. The drug composition comprises the following traditional Chinese medicine in parts by weight: 10 to 30 parts of humulus japonicus, 20 to 30 parts of euphorbia humifusa, 2 to 10 parts of melia azedarach leaves, 20 to 25 parts of herba houttuyniae, 2 to 10 parts of hinoki leaves and 2 to 7 parts of garlic. The invention further discloses a preparation method of the drug composition. According to the drug composition for treating red skin disease of the grass carp, the effective constituents of lupulone and humulone in the humulus japonicus have obvious inhibiting effects on gram positive bacteria such as staphylococcus aureus, streptococcus faecalis, streptococcus pneumoniae, corynebacterium diphtheriae, bacillus anthracis, bacillus subtilis and bacillus cereus in vitro. In the preparation method, a supercritical CO2 extraction method is adopted to extract effective constituents from humulus japonicus, so that activity of the effective constituents of the humulus japonicus is reserved, and the content is higher. The preparation method provided by the invention is simple and practical, and is suitable for large-scale production.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine for treating fish diseases, in particular to a pharmaceutical composition for treating grass carp red skin disease and a preparation method thereof. Background technique [0002] Grass carp red skin disease is caused by local or most of the body surface of the diseased fish bleeding, inflammation, and peeling off scales, especially on the sides and abdomen of the fish. When the "three diseases" are concurrent, the main symptoms are redness and swelling of the anus, inflammation of the intestinal tract, which is purple-red; rotten gill filaments, increased mucus; The disease can occur throughout the year, and the optimum water temperature for the disease is 25-30°C; the disease is most likely to be caused by damage to the fish body due to improper feeding management or parasite parasites on the body surface; Easy to cause disease and epidemic. [0003] The ethanol infusion of the stem...

Claims

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Application Information

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IPC IPC(8): A61K36/8962A61P31/04
Inventor 房元喧王松刚
Owner 泰州市春达动物药业饲料有限公司
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