The invention provides a
humulus japonicus-based functional oral liquid capable of promoting endogenous GLP-1
secretion. The oral liquid is prepared by mixing a
humulus japonicus mixed extracting solution, a suspending aid, a
preservative and water, wherein the
humulus scandens mixed extracting solution is prepared by mixing humulus scandens leaves, humulus scandens roots, humulus scandens stems and radix gentianae and then adding medical
alcohol for extraction. The specific preparation method comprises the following steps: S1, taking fresh humulus scandens leaves, humulus scandens roots, humulus scandens stems and radix gentianae, cleaning,
drying and crushing, putting mixed
powder and medical
alcohol into an extractor, starting
microwave-assisted extraction, separating and sieving after the extraction is completed, concentrating and centrifuging an extracting solution, and taking supernate, so as to obtain a humulus scandens mixed extracting solution; s2, uniformly mixing the humulus scandens mixed extracting solution, a suspending aid, a
preservative and water to obtain the oral liquid. The oral liquid prepared by the invention can remarkably promote
secretion of endogenous GLP-1, is a healthy beverage, can play roles in reducing
blood sugar, losing weight and the like, and further develops the value of humulus plants.