Temperature equalizer for chromatographic columns with stable and uniform working temperatures

Abstract

The invention discloses a temperature equalizer integrated with a plurality of chromatographic columns with different lengths and column diameters. An upper metal heat conduction block and a lower metal heat conduction block are connected with each other through hinges; a plurality of upper semicircular chromatographic column slots and a plurality of lower semicircular chromatographic column slots are respectively formed in the upper metal heat conduction block and the lower metal heat conduction block; one or multiple groups of metal inner bushings are respectively arranged in each of every upper semicircular chromatographic column slot and every lower semicircular chromatographic column slot; one or multiple groups of metal outer bushings are sleeved outside the metal inner bushings; the inner diameters of the metal inner bushings are as the same as the outer diameters of column bodies of the chromatographic columns arranged in the metal inner bushings; the outer diameters of the metal outer bushings are greater than or equal to those of column heads of the chromatographic columns; the lengths of the upper semicircular chromatographic column slots and the lengths of the lower semicircular chromatographic column slots are greater than those of the chromatographic columns. The temperature equalizer is reasonable in structure, can improve the heat conduction efficiency of a high performance liquid chromatograph thermostat, shorten the heat balance time of the high performance liquid chromatograph thermostat and keep the working temperatures of the chromatographic columns consistent, stable and uniform.

Description

[0001] This application is a divisional application with application number: 201210403661.X, application date: 2012.10.22, and name "integrated temperature homogenizer with multiple chromatographic columns of different lengths and column diameters". technical field [0002] The invention relates to a temperature homogenizer integrated with a plurality of chromatographic columns with different lengths and column diameters used in a chromatographic column constant temperature box of a high-performance liquid chromatograph. Background technique [0003] Multidimensional high performance liquid chromatography uses two or more chromatographic columns with different properties to separate components in complex samples. In the detection of multi-dimensional high-performance liquid chromatography, the sample is pre-separated in the first-dimensional chromatographic column, and then all or part of the pre-separated components are selectively transferred to another or more different ty...

AI Technical Summary

Problems solved by technology

The above-mentioned factors that cause the inconsistent, unstable and uneven working temperature of the chromatographic column can affect the accuracy and repeatability of the multidimensional HPLC analysis

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