Temperature equalizer for keeping working temperature of chromatographic column to be uniform

Abstract

The invention discloses a temperature equalizer for keeping the working temperature of a chromatographic column to be uniform. An upper metal heat-conduction block is connected with a lower metal heat-conduction block through a hinge, and a plurality of upper semicircular chromatographic column grooves and a plurality of lower semicircular chromatographic column grooves are respectively formed in the upper metal heat-conduction block and the lower metal heat-conduction block. One or more sets of metal sleeves are respectively arranged in each upper semicircular chromatographic column groove and each lower semicircular chromatographic column groove, the inner diameter of each metal sleeve is the same as the outer diameter of the column body of a chromatographic column placed in the metal sleeve, and the outer diameter of the metal sleeve is larger than or equal to the outer diameter of the column head of the chromatographic column. The length of the upper semicircular chromatographic column groove and the lower semicircular chromatographic column groove is larger than the length of the chromatographic column. The temperature equalizer with a reasonable structure can increase the heat conduction efficiency of an efficient liquid chromatograph thermostat, shorten the heat balance time, and keep the coincidence, stability and uniformity of the working temperature of the chromatographic column.

Description

[0001] This application is a divisional application with application number: 201210397641.6, application date: 2012.10.19, and name "integrated temperature homogenizer with multiple chromatographic columns of different lengths". technical field [0002] The invention relates to a temperature homogenizer integrated with a plurality of chromatographic columns with different lengths used in a chromatographic column constant temperature box of a high performance liquid chromatograph. Background technique [0003] Multidimensional high performance liquid chromatography uses two or more chromatographic columns with different properties to separate components in complex samples. In the detection of multi-dimensional high-performance liquid chromatography, the sample is pre-separated in the first-dimensional chromatographic column, and then all or part of the pre-separated components are selectively transferred to another or more different types of chromatographic columns. column fo...

AI Technical Summary

Problems solved by technology

The above-mentioned factors that cause the inconsistent, unstable and uneven working temperature of the chromatographic column can affect the accuracy and repeatability of the multidimensional HPLC analysis

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