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Chinese medicine composition for treating knee arthritis and preparation method thereof

A composition and technology of traditional Chinese medicine, applied in traditional Chinese medicine composition, traditional Chinese medicine composition for treating knee arthritis and the field of preparation thereof, can solve the problems of obvious gastrointestinal adverse reactions, only the treatment of its symptoms, serious physical injury and the like

Inactive Publication Date: 2014-01-08
GUANGZHOU JIAYUAN PHARMA TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, the drug treatment is mainly to control symptoms, improve the condition, cartilage protection and local external use, etc., mainly to relieve pain and improve motor function. In the past, non-steroidal anti-inflammatory drugs were the main clinical drugs. In recent years, glucosamine hydrochloride has been widely used. These drugs can relieve inflammation and relieve pain, but they cannot change the fundamental pathological changes of osteoarthritis, that is, they can only treat the symptoms, but not the cause; the pain can disappear in a short period of time with anesthesia, but it is easy to recur, and it will last for a long time. Antipyretic, analgesic and hormone drugs are used, which are harmful to the body and have many side effects, and the adverse reactions of the gastrointestinal tract are obvious

Method used

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  • Chinese medicine composition for treating knee arthritis and preparation method thereof
  • Chinese medicine composition for treating knee arthritis and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Embodiment 1 tablet preparation of the present invention

[0015] Take by weighing each crude drug according to the following weight proportions: 180 grams of honeysuckle vine, 120 grams of sumac, 180 grams of Cracker, 120 grams of soil fritillaria, 90 grams of mountain coral, 120 grams of mountain crabapple, 180 grams of Shijincao, 120 grams of mallow leaves for use; mix the above-mentioned Chinese herbal medicines, add 6 times the amount of water to soak for 2 hours, heat and decoct for 1.5 hours, filter, add 5 times the amount of water to the dregs, heat and decoct for 1 hour, filter, and combine twice The filtrate was left to stand for 1 hour, and the supernatant was poured out; when the supernatant was concentrated to 60°C, the relative density was 1.10, and the clear paste was vacuum-dried at 60°C to obtain 100 grams of solids; the solids were crushed and dried, and fine powder was obtained after sieving. Add conventional tablet auxiliary materials to make granule...

Embodiment 2

[0016] Embodiment 2 Granule preparation of the present invention

[0017] Take by weighing each crude drug according to the following weight proportions: 100 grams of honeysuckle vine, 100 grams of sumac, 100 grams of Cracker, 300 grams of soil fritillary, 250 grams of mountain coral, 200 grams of mountain crabapple, 300 grams of Shijincao, 200 grams of mallow leaves for later use; mix the above-mentioned medicinal materials, add 5 times the amount of water to soak for 1.5 hours, heat and decoct for 1 hour, filter, add 4 times the amount of water to the medicinal residues, heat and decoct for 1 hour, filter, and combine the two filtrates , stand still for 1 hour, pour out the supernatant; when the supernatant is concentrated to 60°C, the relative density is 1.08. Conventional granule excipients, made into granules.

Embodiment 3

[0018] Embodiment 3 capsule preparation of the present invention

[0019] Take by weighing each crude drug according to the following weight proportions: 300 grams of honeysuckle vine, 200 grams of sumac, 200 grams of clastaria, 100 grams of soil fritillary, 50 grams of mountain coral, 100 grams of mountain crabapple, 100 grams of stone grass, 50 grams of mallow leaves for later use; mix the above-mentioned medicinal materials, add 5 times the amount of water to soak for 1.5 hours, heat and decoct for 1 hour, filter, add 3 times the amount of water to the dregs, heat and decoct for 1 hour, filter, and combine the two filtrates , stand still for 1 hour, pour out the supernatant; when the supernatant is concentrated to 60°C, the relative density is 1.08, and the clear paste is vacuum-dried at 60°C to obtain 100 grams of solid matter; the solid matter is crushed and dried, and fine powder is obtained after sieving, adding Conventional auxiliary materials are packed into gelatin c...

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Abstract

The invention discloses a Chinese medicine composition for treating knee arthritis and a preparation method thereof, and belongs to the field of traditional Chinese medicine. According to the Chinese medicine composition, active components are prepared from the following traditional Chinese medicinal materials: honeysuckle stem, hematoxylon, lanceolate jasmine root, rhizoma bolbostemmae, galeola faberi, tripterygium hypoglaucum, pilea plataniflora and mallow leaves as raw materials in combination; the active components and auxiliary materials of a common pharmaceutic preparation are prepared into Chinese medicine tablets, granules and capsules. The Chinese medicine composition has an accurate therapeutical effect on the knee arthritis.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating knee arthritis and a preparation method thereof, belonging to the technical field of traditional Chinese medicine. technical background [0002] Knee arthritis is a common joint disease characterized by degeneration of articular cartilage. This disease is a chronic disease characterized by secondary bone hyperplasia on the joint edge and subchondral. It is a common joint disease in middle-aged and elderly people, and can even lead to disability. Knee arthritis takes knee joint pain, stiffness, and dysfunction as the main symptoms, and the progressive degeneration of articular cartilage is the main clinical feature. This disease has a chronic development process, which is related to factors such as age, sex, and body weight; There is no way to completely block the pathological progression of knee osteoarthritis. T...

Claims

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Application Information

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IPC IPC(8): A61K36/63A61P19/02A61P29/00
Inventor 王素侠李威坤
Owner GUANGZHOU JIAYUAN PHARMA TECH
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