Formation process and vacuum drying equipment for direct powder of Tripterygium hypoglaucum roots

Abstract

The invention provides a formation process and vacuum drying equipment for direct powder of Tripterygium hypoglaucum roots, and the process comprises the following steps: (1) crushing: taking a certain amount of Tripterygium hypoglaucum roots, putting the Tripterygium hypoglaucum roots into a crusher, and crushing the Tripterygium hypoglaucum roots into small blocks; (2) extracting a decoction: introducing the decoction into a centrifugal machine, controlling the environment temperature to rise to 80-100 DEG C, then performing ultrasonic vibration on the decoction, and repeating the process for a plurality of times; (3) decoction concentrating: combining the decoction of each time, and concentrating the filtrate into clear paste with the relative density of 1.05-1.07 at the temperature of 50-70 DEG C; (4) standing and filtering: adding ethanol into the clear paste to enable the alcohol content of the clear paste to reach 70-80%, and conducting standing for 12 hours under a low-temperature condition to obtain a second filtrate; and (5) direct powder tabletting: adding the second filtrate into vacuum drying equipment for drying, taking out the dried Tripterygium hypoglaucum root powder, adding starch, pregelatinized starch, talcum powder and magnesium stearate according to the weight ratios of the starch, the pregelatinized starch, the talcum powder and the magnesium stearate to the Tripterygium hypoglaucum root tablets being 0.104-0.109, 0.02-0.05, 0.01-0.02 and 0.003-0.005 respectively, and uniformly conducting mixing.

Description

technical field [0001] The invention relates to the technical field of torch flower root tablet compression molding, in particular to a molding process of torch flower root direct powder and vacuum drying equipment. Background technique [0002] Huobahuagen Tablets are mainly used clinically for rheumatoid arthritis, rheumatoid arthritis, chronic nephritis, lupus erythematosus, traumatic injuries, skin itching, etc. Modern pharmacological studies believe that it has anti-inflammatory and anti-immunosuppressive tumor effects . [0003] At present, the production of Huobahuagen tablets adopts the traditional preparation molding process. The raw materials of Huobahuagen are extracted with suitable solvents, ethanol-precipitated, concentrated into extracts, added with suitable auxiliary materials to make granules, dried, and compressed into tablets. The technological process is roughly as follows: crushing→extraction→concentration→alcohol precipitation→static filtration→concent...

AI Technical Summary

Problems solved by technology

[0004] Aiming at the deficiencies in the prior art, the present invention provides a molding process of torch flower root direct powder and vacuum drying equipment, which solves the problem that the traditional process existing in the prior art suffers from relatively high loss of active ingredients during the tableting process. Too many, can not guarantee the full utilization of medicinal resources

Images