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Traditional Chinese veterinary medicine compound preparation Shuanghuanglian for injection as well as preparation technology and application thereof

A technology of compound preparation and preparation process, which is applied in the field of Shuanghuanglian for injection and its preparation process and application, and can solve the problems such as difficulty in adapting to the frequency of medication in the field of veterinary injection

Inactive Publication Date: 2014-02-19
QINGDAO AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, no sustained-release excipients are added, so it is difficult to adapt to the field of veterinary injections. The frequency of medication is an important direction for the development of new drugs and new preparations.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0018] The preparation process of Shuanghuanglian for injection as a compound preparation of Chinese veterinary medicine:

[0019] (1) Boil Huang Ling with water three times, combine the decoction, adjust the pH to 1.0-2.0, let it stand, filter, add 8 times the water to the precipitate, adjust the pH to 7.0, and add ethanol equal to the volume of water, Stir to dissolve, filter, adjust the pH of the filtrate to 2.0, incubate at 60°C for 30 minutes, let stand, filter, wash the precipitate with ethanol to pH 4.0, add 10 times the volume of water, stir, adjust the pH to 6.0, add 0.5% Activated carbon, stir well, keep warm at 50°C for 30 minutes, add 1 times the volume of ethanol and stir evenly, filter, adjust the pH of the filtrate to 2.0, keep warm at 60°C for 30 minutes, let stand, filter, wash the precipitate with a small amount of ethanol, dry, spare;

[0020] (2) Decoct honeysuckle and forsythia with water twice, filter, concentrate the filtrate to a relative density of 1....

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PUM

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Abstract

The invention relates to a traditional Chinese veterinary medicine compound preparation Shuanghuanglian for injection as well as a preparation technology and an application thereof. The compound preparation comprises the components in parts by weight as follows: 1300-1700 parts of honeysuckle, 1300-3700 parts of radix scutellariae and 2500-7500 parts of fructus forsythiae. Slow-release accessories comprise 150 parts of hydroxymethyl propyl cellulose and 100 parts of sodium carboxymethyl cellulose. The compound preparation contains the slow-release accessories, so that the injection time of large animals can be reduced, and the stress response of the large animals can be reduced. The traditional Chinese veterinary medicine compound preparation for injection has antiviral, antibacterial, anti-inflammatory, antipyretic, analgesic, immunity-improving effects and the like. Veterinarian clinic proves that the compound preparation can be used for treating epidemic diarrhea; transmissible gastroenteritis; necrotic enteritis; septicemia caused by various epidemic diseases; cough, dyspnea, skin cyanosis, arthrocele which are caused by chromic respiratory diseases such as streptococcosis, haemophflussuis, contagious porcine pleuropneumonia, swine plague and the like; and porcine reproductive and respiratory syndrome and cow mastitis.

Description

technical field [0001] The invention relates to a Chinese medicine compound preparation for veterinary injection, in particular to Shuanghuanglian for injection as a Chinese medicine compound preparation and its preparation process and application. Background technique [0002] With the development of society and the continuous improvement of people's living standards, people's dietary structure has undergone great changes, and the demand for animal-derived food is increasing. Moreover, after my country's entry into the WTO, the export trade of livestock and poultry products has increased. It has brought unprecedented prosperity and development to my country's animal husbandry, and the breeding industry has shown a trend of scale and intensification. In order to protect the health of livestock and poultry and increase economic benefits, antibiotics are generally doubled by breeding owners. Food safety issues such as veterinary drug residues caused by drug abuse have become a ...

Claims

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Application Information

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IPC IPC(8): A61K36/634A61K9/19A61K47/38A61P1/12A61P1/00A61P31/04A61P11/14A61P11/00A61P17/00A61P19/02A61P31/12A61P15/14A61P15/00
Inventor 不公告发明人
Owner QINGDAO AGRI UNIV
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