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Compound andrographolidume preparation for veterinary use

A technology of andrographolide, compound andrographis paniculata, applied in medical preparations containing active ingredients, pharmaceutical formulations, climate change adaptation, etc. spectrum antibacterial effect

Active Publication Date: 2015-07-08
胡少平
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Intestinal diseases of domestic animals, such as calf colibacillosis, diarrhea, lamb dysentery, piglet yellow scour, pullorum, swine dysentery, infectious gastroenteritis, epidemic diarrhea, etc., are mostly infectious diseases with fast spread, morbidity and mortality High, if it cannot be cured in time, it will cause great losses to the breeding industry

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0032] 1. Example of Veterinary Compound Andrographolide Injection (parts by weight)

[0033] prescription (1)

[0034] Andrographolide 10 Matrine 5

[0035] Stabilizer 2 Vehicle 983

[0036] Make a total of 1000;

[0037] prescription (2)

[0038] Andrographolide 50 Matrine 25

[0039] Stabilizer 10 Solvent 915

[0040] Make a total of 1000;

[0041] prescription (3)

[0042] Andrographolide 100 Matrine 50

[0043] Stabilizer 20 Solvent 830

[0044] Makes a total of 1000.

[0045] Its preparation method: take an appropriate amount of solvent for injection, stir well; add andrographolide, matrine, and stabilizer in the prescribed amount respectively, and stir to dissolve; add solvent for injection to the full amount, adjust the pH value, filter, pot, and sterilize. Bacteria, lamp inspection, packaging, that is to say.

[0046] 2. Example of Veterinary Compound Andrographolide Granules

[0047] prescription (1)

[0048] Andrographolide 10 Matrine 5

[0049] ...

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Abstract

The invention discloses a compound andrographolidume preparation for veterinary use. The compound andrographolidume preparation comprises the following components in parts by weight: 10-100 parts of andrographolidume, 5-50 parts of sophocarpidine, 0-20 parts of a stabilizer, 0-985 parts of a solvent and 0-985 parts of auxiliary materials. The compound preparation prepared from two traditional Chinese medicine effective ingredients of the andrographolidume and the sophocarpidine as main drugs has better broad-spectrum antibacterial and anti-viral effects and has different inhibition effects on shigella dysenteriae, escherichia coli, staphylococcus aureus, diplococcus pneumoniae, streptococcocci, various viruses and the like; the sophocarpidine is an alkaloid effective ingredient extracted from sophors flavescens ait and has a remarkable inhibition effect on shigella dysenteriae, escherichia coli, salmonella, proteusbacillus vulgaris, staphylococcus aureus, streptococcocci and amebic protozoa; the clinical treatment effect of the compound preparation on intestinal diseases of livestock is remarkable and superior to that of a prescribed preparation of a prescription medication of the compound preparation.

Description

technical field [0001] The invention relates to a veterinary compound andrographolide preparation for treating intestinal diseases of domestic animals. Background technique [0002] Intestinal diseases of domestic animals, such as calf colibacillosis, diarrhea, lamb dysentery, piglet yellow scour, pullorum, swine dysentery, infectious gastroenteritis, epidemic diarrhea, etc., are mostly infectious diseases with fast spread, morbidity and mortality If it cannot be cured in time, it will cause great losses to the aquaculture industry. Various veterinary medicines are of a great variety at present, and effect is different. Contents of the invention [0003] The object of the present invention is to provide a veterinary compound andrographolide preparation with remarkable curative effect, no drug resistance and safe use and a preparation method thereof. [0004] Veterinary compound andrographolide preparation of the present invention comprises andrographolide, matrine, stabi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/4375A61P1/12A61P31/04A61K31/365
CPCY02A40/70
Inventor 胡少平
Owner 胡少平
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