Preparation method of silver ion hydrogel dressing

Abstract

The invention relates to a preparation method of silver ion hydrogel dressing. The method comprises the following steps: firstly, a hydrophilic high-molecular polymer aqueous solution is prepared, and is subjected to vacuum defoamation for standby; secondly, the hydrophilic high-molecular polymer aqueous solution obtained in the first step is prepared into a hydrogel material semi-finished product through a coating method or an injection molding method; thirdly, the hydrogel material semi-finished product is prepared into hydrogel material through the radiation of high energy ray; fourthly, the hydrogel material is dipped into silver salt aqueous solution, so that the hydrogel material absorbs silver ion loaded in the silver salt aqueous solution, and then the silver ion hydrogel dressing is obtained. The prepare silver ion hydrogel dressing prepared through the method has good biocompatibility, is non-irritative and non-sensitized to skin, provides wet healing environment for wound healing, promotes wound healing, moreover can slowly release silver ion, effectively restrains and prevents the growth of common bacteria on the wound, and can be applied to nursing of various acute and chronic wounds.

Description

technical field [0001] The invention relates to the technical field of dressing preparation, in particular to a preparation method of a silver ion hydrogel dressing. Background technique [0002] Traditional dressings represented by gauze bandages are currently the most widely used dressings in trauma clinics. Their strong ability to absorb wound exudate has a certain protective effect on wounds and can prevent exudate accumulation. The wound surface will adhere to the wound surface, which will cause secondary damage to the wound surface when changing the dressing, and slow down the wound healing speed. With the introduction of the theory of moist healing, a new generation of dressings that can provide a moist healing environment such as alginate, hydrocolloid, and hydrogel have significant therapeutic and nursing effects, and are widely recognized and widely used. [0003] Hydrogel is a polymer compound with a three-dimensional network structure, which can absorb and slowl...

AI Technical Summary

Problems solved by technology

Traditional wound care products with silver as the active ingredient, represented by silver sulfadiazine, have a very low utilization rate of silver. In order to ensure the therapeutic effect, a large dose of silver needs to be added, which causes waste of resources and promotes pigmentation on the wound surface. , silver poisoning and other negative effects

Recently, products made by spraying silver on support materials such as gauze and alginate fibers have appeared. These products replace the silver components in the products with body fluids exuded from the wound to achieve antibacterial effects, but such dry dressings only Applicable to wounds with exudate, the scope of use is limited