Traditional Chinese medicine composition for achieving liver-protection and pain-easing effects and preparation method thereof

A composition and technology of traditional Chinese medicine, applied in the field of liver-protecting and pain-relieving traditional Chinese medicine composition and preparation thereof, can solve the problems of low extraction rate, influence on drug efficacy, unable to propose active ingredients, etc., and achieve excellent analgesic effect and good protective effect , the effect of orderly arrangement of hepatocyte cords

Active Publication Date: 2014-04-09
GUANGXI WUZHOU PHARMA GRP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0018] Due to the different properties of the active ingredients in the eight-flavored medicinal materials, if the preparation methods in the above patents all use water extraction, some active ingredients cannot be extracted, or the extraction rate is low, which will affect the efficacy of the drug.

Method used

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  • Traditional Chinese medicine composition for achieving liver-protection and pain-easing effects and preparation method thereof
  • Traditional Chinese medicine composition for achieving liver-protection and pain-easing effects and preparation method thereof
  • Traditional Chinese medicine composition for achieving liver-protection and pain-easing effects and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0068] 1) Take the following medicinal materials in parts by weight: 456g of Desmodium glabra, 302g of Corn Stigma, 228g of Shiwei, 228g of Chicken Bone Grass, 228g of Poria Cocos, 165g of Plantain, 165g of Sea Golden Sand Grass, 228g of Imperata Rhizome;

[0069] 2) Desmodium radix, Shiwei, and Jigucao were extracted twice with sodium bicarbonate solution with a mass-volume percentage of 0.1%, each time adding sodium bicarbonate solution of 20 times and 15 times the total weight of the medicinal materials, and extracted each time The time is 4 hours and 2 hours respectively, the extracts are combined, filtered, and the filtrate is concentrated into a liquid extract;

[0070] 3) Imperata cocos, Poria cocos, plantain, corn silk, and sea ginseng are extracted twice with water, each time adding water 12 times and 10 times the total weight of the five flavors of traditional Chinese medicine, and decocting for 3 hours and 2 hours each time, respectively. Combine the decoctions, fil...

Embodiment 2

[0073] 1) Take the following medicinal materials in parts by weight: 456g of Desmodium glabra, 302g of Corn Stigma, 228g of Shiwei, 228g of Chicken Bone Grass, 228g of Poria Cocos, 165g of Plantain, 165g of Sea Golden Sand Grass, 228g of Imperata Rhizome;

[0074] 2) Desmodium radix, Shiwei, and Jigucao were extracted 3 times with sodium bicarbonate solution with a mass-volume percentage of 1%, and sodium bicarbonate solution was added 20 times, 15 times, and 10 times the total weight of the medicinal materials respectively, The extraction time is 4 hours, 2 hours, and 1 hour respectively, the extracts are combined, filtered, and the filtrate is concentrated into a liquid extract;

[0075] 3) Add water to extract the root of rhizoma imperinae, poria cocos, plantain, corn silk, and sea ginseng 3 times, each time adding 12 times, 10 times, and 6 times the total weight of five flavors of traditional Chinese medicine, and decocting for 3 hours each time. After 2 hours and 1 hour, ...

Embodiment 3

[0078] 1) Take the following medicinal materials in parts by weight: 456g of Desmodium glabra, 302g of Corn Stigma, 228g of Shiwei, 228g of Chicken Bone Grass, 228g of Poria Cocos, 165g of Plantain, 165g of Sea Golden Sand Grass, 228g of Imperata Rhizome;

[0079] 2) Desmodium radix, Shiwei, and Jigucao were extracted 3 times with sodium bicarbonate solution with a mass-volume percentage of 0.5%, and sodium bicarbonate solution was added 20 times, 15 times, and 10 times the total weight of the medicinal materials respectively, The extraction time is 3 hours, 2 hours, and 1 hour respectively, the extracts are combined, filtered, and the filtrate is concentrated into a liquid extract;

[0080] 3) Imperata cocos, Poria cocos, plantain, corn silk, and sea ginseng are extracted with water for 3 times, each time adding 10 times, 8 times, and 8 times the total weight of five flavors of traditional Chinese medicine, and decocting for 3 hours and 8 times each time. 2 hours, 2 hours, co...

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Abstract

The invention relates to a traditional Chinese medicine composition for achieving liver-protection and pain-easing effects and a preparation method of the traditional Chinese medicine composition. The preparation method comprises the steps of taking eight medicinal materials including Desmodium styracifolium, corn stigma, pyrrosia lingua, Abrus cantoniensis Hance, Poria cocos, plantain herb, Lygodium japonicum Sw and lalang grass rhizome, wherein the Desmodium styracifolium, the pyrrosia lingua and the Abrus cantoniensis Hance are extracted by an alkaline aqueous solution, and the lalang grass rhizome, the Poria cocos, the plantain herb, the corn stigma and the Lygodium japonicum Sw are extracted by water; and finally mixing fluid extracts obtained by the two extraction methods. The animal pharmacological experiments and clinical test results prove that the traditional Chinese medicine composition has excellent liver-protection and pain-easing effects superior to the prior art when being used for treating lithiasis in urinary system.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating calculi in the urinary system, in particular to a liver-protecting and analgesic Chinese medicine composition and a preparation method thereof. Background technique [0002] Urinary system stones belong to the scope of "sand stranguria", "stone stranguria" and "blood stranguria" in TCM gonorrhea, mainly including 4 syndrome types: [0003] (1) Qi stagnation and blood stasis type: Symptoms include dull pain in the waist, dull pain, normal or tight pulse, and normal tongue; or sudden interruption of urination during drowning, severe pain that extends to the waist and abdomen, and the pain is relieved after the discharge of sand and stones; or Pain in the waist and flanks, which is like twisting, causing the lower abdomen, frequent attacks, pale complexion, cold sweat, nausea, accompanied by blood in the urine or yellowish urine, dark red tongue or petechiae, ecchymosis, stri...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P13/04A61P1/16A61P29/00
Inventor 张栩颜刘冠萍郑志远林艳英黎思慧钟杰敏林双
Owner GUANGXI WUZHOU PHARMA GRP
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