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Traditional Chinese medicine effective part composition for treating recurrent aphthae

A technology for recurrent aphthous ulcers and effective parts, which can be used in drug combinations, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve the problems of immune dysfunction, lack of specific treatments, etc., and achieve the effect of not easy to recur

Inactive Publication Date: 2014-05-07
广州市云桥生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The cause of this disease has not been clarified so far, it may be related to viral or bacterial infection, immune dysfunction, endocrine disorder or genetic factors, modern western medicine still lacks effective treatment for this disease

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] 22g of golden fruit olive, 20g of white perilla seed, 16g of stiff pupae, 15g of Fushen, 13g of bean root and 14g of sala seed, after drying, add 12 times the amount of water, boil with strong fire, then decoct with slow fire for 180min, the obtained soup Dosage spare.

Embodiment 2

[0015] 500 patients with recurrent aphtha were clinically observed. All patients were diagnosed as recurrent aphtha by clinical diagnosis. Take embodiment 1 gained decoction to the patient, 1 day 2 times, take before meal sooner or later, continuously 7 days.

[0016] The statistical results of patients taking the decoction gained in Example 1 are shown in Table 1. Significant effect includes recovery and effectiveness. Recovery means that the clinical symptoms and signs disappear, and there is no recurrence after follow-up for more than one year; effective means that the pain of aphthous sores is significantly relieved, breaking the previous attack pattern, and the interval period is extended within 6 months without recurrence. Ineffective means that after treatment, the number, shape and pain of aphthous ulcers, the interval between attacks and systemic symptoms have no obvious improvement.

[0017] Table 1

[0018] Number of cases markedly effective invalid...

Embodiment 3

[0021] The decoction prepared in Example 1 was used to administer ICR mice with a body weight of 20-25 g, half male and half female, and the administration was continued for 60 days.

[0022] After preliminary testing, the toxicity of the decoction prepared in Example 1 was very low, and the LD50 could not be detected, so the maximum daily dose was determined for mice. The maximum dosage is 400ml / d. After 60 days, there is no case of poisoning death, and all of them are healthy and alive. This proves that the decoction made from the composition of the present invention has no toxic side effects on the human body.

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PUM

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Abstract

The invention discloses a traditional Chinese medicine effective part composition for treating recurrent aphthae. The traditional Chinese medicine effective part composition comprises the raw materials of radix tinosporae, perilla frutescens, beauveria bassiana vuill, poria with hostwood, asiatic moonseed rhizome and semen aesculi in certain parts by weight, The traditional Chinese medicine effective part composition provided by the invention has the effects of clearing away heat and purging pathogenic fire, eliminating evil and relieving internal heat or fever, nourishing yin and clearing heat, decreasing internal heat and heeling sore, warming yang and strengthening body resistance, tonifying qi and relieving pain and activating blood circulation to dissipate blood stasis, is remarkable in curative effect on treatment of the recurrent aphthae, and high in safety, and has no side effects.

Description

[0001] technical field [0002] The invention relates to the field of traditional Chinese medicine compositions, in particular to a composition of effective parts of traditional Chinese medicines for treating recurrent aphthous ulcers. Background technique [0003] Recurrent aphth is the most common ulcerative lesion in oral mucosal disease, which has the characteristics of periodic outbreaks. The etiology of this disease is not clear so far, and it may be related to viral or bacterial infection, immune dysfunction, endocrine disorders or genetic factors. Modern Western medicine still lacks specific treatments for this disease. Contents of the invention [0004] The object of the present invention is to provide a traditional Chinese medicine effective part composition for treating recurrent aphthous ulcer, the effective part composition can treat recurrent aphthous ulcer and is not easy to relapse. [0005] The above-mentioned purpose of the present invention is achieved...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/59A61P1/02A61K35/64
Inventor 张群
Owner 广州市云桥生物科技有限公司
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