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Application of Buyi Zisheng pill in preparation of drug used for treating depression

A technology for nourishing Zisheng pills and depression, applied in the field of medicine, can solve the problems of easy drug dependence, easy recurrence, sexual dysfunction, etc., and achieve the effects of ideal long-term curative effect, less adverse reactions, and low recurrence rate.

Inactive Publication Date: 2014-07-09
刘洪军 +1
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

These drugs have a certain curative effect, but these drugs are prone to drug dependence, and the symptoms are improved when taking the drugs, and they are easy to relapse after stopping the drugs.
In addition, patients are also prone to side effects such as dry mouth, poor appetite or constipation, insomnia, nausea, and sexual dysfunction, which reduce the quality of life of patients.

Method used

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  • Application of Buyi Zisheng pill in preparation of drug used for treating depression

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specific Embodiment approach

[0010] Clinical Data of Buyi Zisheng Pills in Treating Parkinson's Disease

[0011] 1 clinical data

[0012] 1.1 Objects and methods

[0013] 1.1.1 The subjects were outpatients in our hospital, all of whom were in line with the diagnostic criteria for depression in the "Chinese Classification and Diagnostic Criteria of Mental Disorders" (3rd Edition), with scores of 17 items on the Hamilton Depression Scale (HAMD) ≥ 18 points. There were 82 cases in the Chinese medicine treatment group, with an average age of (54.21±14.78) years; 38 males and 44 females. There were 70 patients in the western medicine group, with an average age of (55.32±15.63) years; 29 males and 41 females. There was no difference in the mean values ​​of HAMD depression scale and TCM symptom scores between the two groups at baseline (P>0.05). There was no statistical difference in gender and age composition between the two groups (P>0.05), and they were comparable. The above subjects all completed the ob...

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Abstract

The invention belongs to the technical field of medicine and relates to novel application of a Chinese patent medicine, specifically to application of the Buyi Zisheng pill in preparation of a drug used for treating depression. The prescription of the Buyi Zisheng pill comprises ginseng, bighead atractylodes rhizome (stir-fried with bran), Poria cocos, licorice, white hyacinth bean (peeled), Chinese yam, fructus crataegi cuneatae (stir-fried), medicated leaven (stir-fried with bran), malt, lotus seed, coix seed (stir-fried with bran), gordon euryale seed (stir-fried with bran), oriental waterplantain rhizome, cardamom, pummelo peel, cablin patchouli herb, balloonflower root and coptis. The preparation method for the Buyi Zisheng pill comprises the following steps: crushing the above-mentioned 18 traditional Chinese medicines into fine powder and carrying out sieving and uniform mixing; and adding 130 to 140 g of refined honey into each 100 g of powder so as to prepare a big honey pill, i.e., the Buyi Zisheng pill. The Buyi Zisheng pill is capable of nourishing yin, tonifying Qi and nursing the spleen and the stomach. It is currently found that oral administration of the Buyi Zisheng pill exerts a treatment effect on depression.

Description

technical field [0001] The invention belongs to the technical field of medicine and relates to a new application of a Chinese patent medicine, in particular to the application of Buyi Zisheng Pills in the preparation of medicines for treating depression. Background technique [0002] With the development of society, people are under increasing pressure from all aspects, and depression has become a common clinical disease. The disease is currently mainly treated with psychological counseling and medication. Drug therapy is the main treatment in our country. The most commonly used drugs in clinical practice are ① tricyclic antidepressants, including imipramine, amitriptyline, clomipramine, and doxepin (doxepin), which are currently better antidepressants, among which Amitriptyline is the most commonly used. ②Tetracyclic antidepressants, such as maprotiline, are commonly used in clinical practice. Its role is similar to that of tricyclics. ③Selective serotonin reuptake inh...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9064A61K9/20A61P25/24
Inventor 常美郑鑫石鑫
Owner 刘洪军
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