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Drug for chronic hepatitis B and preparation method thereof

A technology for chronic hepatitis B and medicine, applied in the field of chronic hepatitis B medicine and its preparation, can solve the problems of high price, high morbidity, easy repetition, etc., and achieve the effects of improving clinical symptoms, definite curative effect and stable process

Active Publication Date: 2016-11-23
合肥同康堂医疗健康管理有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Chronic hepatitis B is a common disease with high morbidity, long course, and easy recurrence. The treatment methods of modern medicine for CHB mainly include liver protection, enzyme reduction, anti-virus, etc., but there are certain side effects, drug resistance, easy Repeated, expensive and other shortcomings

Method used

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  • Drug for chronic hepatitis B and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] 1. Formulation

[0024] Adenophora 166.7g Ophiopogon japonicus 166.7g Rehmannia glutinosa 333.3g Lycium barbarum 166.7g Pseudostellaria 133.3g Schisandra 133.3g Astragalus 133.3g Bupleurum 133.3g Capillary 166.7g Angelica 133.3g Salvia 133.3g Radix 133.3g Sanqi 166.7g Sanqi Rib 100g Sun-fried turtle shell 100g Sophora flavescens 133.3g Rhubarb 133.3g Licorice 100g

[0025] 2. Preparation method

[0026] The above eighteen flavors, Ophiopogon japonicus, Radix Pseudostellariae, Schisandra chinensis, Salvia miltiorrhiza, Radix Paeoniae Rubra, Panax notoginseng were extracted by adding 10 times the amount of 70% ethanol twice, each time for 2 hours, filtered, combined filtrates, recovered ethanol and concentrated to a relative density of 1.32 (heat test at 80°C) thick ointment, herbal dregs and the other twelve flavors such as Adenophora pilosulae, etc., add 10 times the amount of water and decoct twice, 2 hours each time, combine the decoction liquid, filter, and concentr...

Embodiment 2

[0048] Embodiment 2: clinical research

[0049] All the data are from August 2006 to February 2008, who were admitted to the outpatient and inpatient wards of Anhui Red Cross Cardiovascular Disease Hospital, who met the criteria of mild and moderate chronic hepatitis B diagnosed by Western medicine and the diagnostic criteria of liver and kidney yin deficiency in traditional Chinese medicine. 120 patients.

[0050] 1. Case selection criteria

[0051] 1.1. Western medicine diagnostic criteria: in line with the 2005 "Guidelines for the Prevention and Treatment of Chronic Hepatitis B" diagnostic criteria.

[0052] 1.2. Diagnostic criteria of TCM syndromes

[0053] 1.2.1 Liver and Kidney Yin Deficiency Syndrome

[0054] Main symptoms: hypochondriac dull pain, soreness of waist and knees, dry mouth and throat, hot hands, feet, heart, red tongue, little or no fur.

[0055] Secondary symptoms: low fever, dizziness, dry eyes, insomnia and dreaminess, thready and rapid pulse.

[0...

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Abstract

The invention relates to a chronic hepatitis B drug and a preparation method thereof. The drug comprises Coastal Glehnia Root, Ophiopogon japonicus, radix rehmanniae, Chinese wolfberry, Pseudostellaria heterophylla, schisandra chinensis, astragalus, radix bupleuri, artemisia capillaries, angelica, Salvia Miltiorrhiza, radix paeoniae rubra, panax pseudoginseng, Sparganium stoleniferum, grilled turtle shell, sophora flavescens, rhubarb and licorice. The drug provided by the invention has the effects of nourishing liver and kidney, soothing liver and regulating qi, promoting blood circulation and removing blood stasis, is suitable for liver-kidney yin deficiency type chronic hepatitis B, and can obviously improve the liver function, alleviate liver fibrosis, and reduce the blood fat-globulin level, thus being worthy of popularization and application in clinical trials.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine compositions, and more specifically relates to a medicine for chronic hepatitis B and a preparation method thereof. Background technique [0002] Chronic viral hepatitis B (CHB) is a common infectious disease caused by hepatitis B virus (HBV). There are about 350 million people infected with hepatitis B virus in the world, and about 120 million people are infected in China. About 100 million people are infected every year. Thousands of people die from liver failure, liver cirrhosis and primary liver cancer caused by HBV infection. [0003] Chronic hepatitis B belongs to the categories of "jaundice", "hypochondriac pain", "liver plague" and "accumulation" in traditional Chinese medicine. All aspects are interconnected and affect each other. When chronic hepatitis B is repeatedly active for a long time and does not heal for a long time, even when there is the possibility of ea...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/902A61P1/16A61P31/20A61K35/586
Inventor 吴侠蒋军
Owner 合肥同康堂医疗健康管理有限公司