Dissolving solid solution perforator patch for migraine treatment
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A soluble and solid solution technology, applied in non-central analgesics, prostheses, needles, etc., can solve problems such as limitations of nasal spray administration, and achieve the effect of reducing side effects
Inactive Publication Date: 2014-07-30
THERAJECT INC.
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For faster efficacy, nasal spray administration can be used, but nasal spray administration also has significant limitations
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[0038] With reference to the detailed embodiments of the invention, the embodiments will cooperate with the accompanying Figure 1 , wherein like reference numerals designate like elements throughout. The embodiments described below explain the present invention by referring to the figures.
[0039] The practice of the present invention will employ, unless otherwise indicated, conventional methods of engineering, chemistry, biochemistry, pharmacology and drug delivery, which are within the skill of the art. The literature will fully explain these techniques. All publications, patents and patent applications cited herein, whether supra or infra, are hereby incorporated by reference in their entirety.
[0040] According to at least one embodiment of the present invention, a soluble solid solution perforated (SSP) patch can be used to effectively treat migraine with relatively small doses. The dissolvable SSP patch may contain anti-migraine drugs, such as dihydroergotamine, tr...
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Abstract
A dissolving solid solution perforator (SSP) patch for oral cavity administration may include at least one perforator. The at least one perforator may contain a first drug and be configured to pierce an outside layer of an oral cavity for promptly delivering the first drug. The at least one perforator may penetrate an epithelium layer of the oral cavity and to deliver the antimigraine drug into blood vessels in a submucosa layer.
Description
[0001] Cross Reference for Online Application [0002] This application claims priority under 35 USC § 119(e) of US Provisional Application No. 61 / 552,792, filed October 28, 2011, which is hereby incorporated by reference in its entirety. [0003] The subject matter of this application is U.S. Patent Application No. 11 / 991,682, filed April 28, 2008, Attorney Docket: (840.0001), U.S. Patent Application No. 13 / 364,438, filed 2012-2 Attorney's Docket No.: (840.0002), U.S. Patent Application No. 11 / 285,669, filed Nov. 21, 2005, Attorney's Docket No.: (840.0004), U.S. Patent Application No. 10 / 767,359 , filed January 28, 2004, Attorney Docket No.: (840.0006), and U.S. Patent Application No. 10 / 179,749, filed June 25, 2002, Attorney Docket No.: (840.0003), hereby Its entire contents are incorporated by reference. technical field [0004] The present invention relates to a soluble solid solution perforated (SSP) patch, and more particularly, to a soluble SSP patch for treating migr...
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