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Application of fordia cauliflora extract

A kind of dried pinto bean and extract technology, applied in the application field of dried pinto bean extract

Inactive Publication Date: 2014-08-06
GUANGXI INST OF BOTANY THE CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Modern pharmacological studies have shown that dried pinto bean has anti-inflammatory, anti-oxidation, anti-aging, and memory-improving effects, but there is no report on its use as a single component or in combination with other components for the prevention and treatment of hyperlipidemia

Method used

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  • Application of fordia cauliflora extract
  • Application of fordia cauliflora extract
  • Application of fordia cauliflora extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0014] The following experiment will further illustrate the effect of dried pinto bean extract on the treatment of hyperlipidemia.

[0015] 1. Effect of dried pinto bean extract on blood lipids in aging mice

[0016] 1. Experimental materials and methods

[0017] 1.1 Drugs and reagents

[0018] Dried pinto beans were purchased from Babu District, Hezhou, Guangxi; superoxide dismutase (SOD), malondialdehyde (MDA), total antioxidant capacity (T-AOC) assay kits, Nanjing Jiancheng Bioengineering Institute; total cholesterol ( TC), triglyceride (TG) assay kits, Sichuan Mike; D-galactose, bioshapr company; the rest of the reagents are domestic analytical grade.

[0019] 1.2 Instruments

[0020] TGL-16R high-speed refrigerated centrifuge Zhuhai Heima Company; RT-9100 semi-automatic biochemical analyzer Shenzhen Leidu Life Science Co., Ltd.; electronic balance, Mettler-Toledo Instruments Shanghai Co., Ltd.

[0021] 1.3 Experimental animals

[0022] BALB / C mice, SPF grade, weighin...

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Abstract

The invention discloses novel application of a fordia cauliflora extract in the field of pharmacy, and particularly discloses application of the fordia cauliflora extract in preparing medicaments for treating hyperlipidemia. The fordia cauliflora extract is a fordia cauliflora alcohol extract or a fordia cauliflora aqueous extract. On the basis of massive experiments, the applicant discovers that the fordia cauliflora alcohol extract or the fordia cauliflora aqueous extract can be used for remarkably reducing the level of total cholesterol and / or triglyceride and reducing the low-density lipoprotein cholesterol level, can be applied to medicaments for treating hyperlipidemia as a single active component or combination with other active components, and does not have toxic or side effect to a body.

Description

technical field [0001] The invention relates to the application of plant extracts, in particular to the application of dried pinto bean extracts. Background technique [0002] Blood lipids are the general term for neutral fats (cholesterol, triglycerides) and lipids (sterols, steroids, phospholipids, glycolipids) in plasma, which widely exist in animals and humans. Generally speaking, blood lipids mainly refer to triglycerides and cholesterol, among which cholesterol is mainly used to synthesize cell plasma membranes, steroid hormones and bile acids, while triglycerides participate in energy metabolism in the human body. Blood lipid content can reflect the situation of lipid metabolism in the body. Hyperlipidemia generally means that the serum total cholesterol (TC) level is too high, the serum triglyceride (TG) level is too high, or both indicators are too high. At present, the prevalence rate of hyperlipidemia is about 25% among people over 35 years old in our country. ...

Claims

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Application Information

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IPC IPC(8): A61K36/48A61P3/06
Inventor 杨子明
Owner GUANGXI INST OF BOTANY THE CHINESE ACAD OF SCI
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