Method for producing L-threonine through fermentation of bacteria changing regulatory element of aconitase
A technology of regulating elements and aconitase, which is applied in the field of amino acid fermentation, can solve the problems of difficulty in bacterial growth, long metabolic distance, and that regulating elements cannot be simply improved or knocked out, and achieves the effect of facilitating popularization and application and increasing yield.
CN103993048AActive Publication Date: 2014-08-20INNER MONGOLIA EPPEN BIOTECH CO LTD
Patent Information
- Authority / Receiving Office
- CN ยท China
- Current Assignee / Owner
- INNER MONGOLIA EPPEN BIOTECH CO LTD
- Publication Date
- 2014-08-20
Abstract
The invention provides a method for producing L-threonine through fermentation. The method comprises the steps of transforming the wild type regulatory element of an acnA gene on bacterial chromosome, so that the expression quantity of the aconitase A is lowered, but not disappear; and producing L-threonine through fermentation of the transformed bacteria. In addition, the invention also provides methods and applications derived from the method for producing L-threonine through fermentation, and bacteria used in the methods and applications.
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Claims
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