A preparation method of bone biorepair preparation with inducible gene expression

A bioremediation and gene expression technology, which is applied in drug combinations, pharmaceutical formulas, cosmetic preparations, etc., can solve problems such as the inability to repair damaged teeth and the inability to meet the needs of medical development

Active Publication Date: 2015-10-07
北京幸福益生高新技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

The third category: pharmaceutical toothpaste, for different conditions such as periodontitis; simple hemostasis function, unable to repair damaged teeth
Far from meeting the needs of medical development

Method used

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  • A preparation method of bone biorepair preparation with inducible gene expression
  • A preparation method of bone biorepair preparation with inducible gene expression
  • A preparation method of bone biorepair preparation with inducible gene expression

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Embodiment Construction

[0030] The following embodiments are only used to illustrate the present invention, and the scope of protection of the present invention is not limited only to the following examples. Those of ordinary skill in the technical field can realize the purpose of the present invention according to the disclosure content of the present invention.

[0031] The preparation method of preparation of the present invention comprises the steps:

[0032] (1) Preparation of calcium oxide: take limestone and seal it in a platinum pot, calcinate at a high temperature at 1900°C, and pulverize it into CaO powder of 10-20nm after cooling;

[0033] (2) Generate biologically active hydroxyapatite: take CaO and P with specifications of 10-20nm 2 o 5 Nano-powder, according to the mass ratio of 1:1.67, mix evenly into 500g of powder, under the condition of 36-38℃, age for at least 12 hours in the dark; add 500g of medical pure water and stir to form a paste, then add Na 2 o 2 (3g) stirred at 38°C f...

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Abstract

The invention relates to a preparation method of a bone bioremediation preparation with induced gene expression. The prepared biomaterial can be used for manufacturing biological bone repair toothpaste, tissue engineering regeneration, injury repair medical material and the like; and in particular, the biomaterial has important scientific value and significance on the aspects of tissue engineering bone, peripheral nerve, blood vessel, tendon, in vitro artificial liver artificial kidney device, tissue engineering mouth mucosa, bone repair material, dental caries prevention, gomphiasis, bleeding gums, oral rehabilitation and injury repair, and makes important contribution to the human tissue generation engineering.

Description

technical field [0001] The invention relates to a preparation method of a biorepair preparation with inducible gene expression, in particular to a bioactive preparation which can be used continuously for a long time to solve problems such as bone repair. The product of the invention can be used to manufacture biological bone repairing toothpaste, tissue engineering regeneration, wound repairing medical materials and the like. Can be widely used in: tissue engineering bone, peripheral nerve, blood vessel, tendon, extracorporeal artificial liver and artificial kidney device, tissue engineering oral mucosa, bone repair material, prevention of dental caries, loose teeth, bleeding gums, tooth restoration, trauma repair, etc. widely used. Background technique [0002] 1. Toothpaste market: [0003] In today's toothpaste market in China, my country produces about 8 billion standard sticks of toothpaste (65 gram packages) each year, realizing a total output value of 14 billion yua...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L27/12A61L27/02A61L27/54A61K8/24A61K8/25A61Q11/00A61P1/02
Inventor 胡方
Owner 北京幸福益生高新技术有限公司
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