Additive composition containing lysozyme

Abstract

The invention discloses an additive composition containing lysozyme. The additive composition containing the lysozyme comprises the following various components in percentages by mass: 0.01-3% of a zinc-containing compound, 0.001-3% of the lysozyme and 1-30% of hydroxyapatite. The zinc-containing compound is used with the lysozyme, on one aspect, the oral local serum zinc concentration can be increased, bacterial colonization in the oral cavity of a user is reduced through zinc ions by inhibiting interaction between bacterial glucose metabolism and bacterial cell walls, and moreover, in the presence of the zinc ions, the sterilizing and antibacterial effects of the lysozyme can be enhanced; and on the other aspect, by combination of the zinc-containing compound and the lysozyme, metallic taste and acerbity which are caused by zinc salt can be covered and reduced well. In addition, by the additive composition, the hydroxyapatite is compounded into the composition of zinc citrate and thelysozyme according to a specific ratio, the stability of the effect can be improved remarkably, bacteria are inhibited for a long time, dental plaques are reduced, bleeding gums are relieved, and theadditive composition containing the lysozyme can be used for preparing an oral nursing article.

Description

technical field [0001] The invention relates to the technical field of lysozyme application, in particular to an additive composition containing lysozyme. Background technique [0002] Oral problems are mainly caused by bacteria. Using effective mouthwash, toothpaste and treatment of oral diseases can significantly reduce the number of pathogenic bacteria in the oral cavity, improve or even eliminate oral diseases. Oral care products such as mouthwash and toothpaste can achieve these functions mainly by the active ingredients or antibacterial ingredients in the products. These antibacterial ingredients are mostly Chinese herbal medicines and chemical antibacterial agents. Chemical antibacterial agents such as triclosan , cetylpyridinium chloride, chlorhexidine, antibiotics, etc. Frequent use of oral care products containing these ingredients is likely to cause oral bacterial ecological imbalance, or cause bacteria to develop drug resistance, which cannot prevent oral disease...

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Problems solved by technology

In addition, many studies have also shown that zinc deficiency is one of the most important pathogenic factors of recurrent aphthous ulcers. Therefore, adding zinc salts to oral care products is beneficial to the treatment of recurrent aphthous ulcers. However, zinc salts have a very strong metallic, bitter and astringent taste. , especially when oral care products contain high doses of zinc salts

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