External use drug capable of improving microcirculation, clearing and activating channels and collaterals, promoting blood circulation removing stasis and treating rheumatism bone diseases and preparation method thereof
A technology for promoting blood circulation and removing blood stasis, rheumatic bone disease, applied to medical preparations containing active ingredients, bone diseases, drug combinations, etc., can solve problems such as gastric irritation, liver and kidney functions, and improve safety, Improvement of extract quality and effect of improving microcirculation in mice
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Embodiment 1
[0029] A medicine for external use capable of improving microcirculation, dredging meridians and collaterals, promoting blood circulation and removing blood stasis, and treating rheumatic bone disease, which is made into granules of the following raw materials in parts by weight: 10 parts of Passepartout, 8 parts of Fangfeng, and 8 parts of Atractylodes atractylodes , 8 parts of Angelica, 8 parts of Artemisia argyi, 8 parts of Duhuo, 8 parts of Spatholobus, 10 parts of Polygonum cuspidatum, 10 parts of Epimedium, 10 parts of Eucommia, 4 parts of Guizhi, 4 parts of Safflower, and 4 parts of Sappan.
[0030] Preparation method: Take 4 traditional Chinese medicinal materials of Fangfeng, Duhuo, Epimedium, and Sappan, and cut them into 10-15mm sections. Mix it with the above 4 traditional Chinese medicinal materials, put it in a heat reflux extraction tank, add water to soak for 1 hour, heat reflux extraction for 5 hours, concentrate to a specific gravity of 1.15-1.20, dry at 80°C,...
Embodiment 2
[0032] A medicine for external use capable of improving microcirculation, dredging meridians and collaterals, promoting blood circulation and removing blood stasis, and treating rheumatic bone disease, which is made into granules of the following raw materials in parts by weight: 7 parts of Passepartout, 9 parts of Fangfeng, and 9 parts of Atractylodes , 9 parts of Angelica, 9 parts of Artemisia argyi, 9 parts of Duhuo, 9 parts of Caulis Spatholobus, 8 parts of Polygonum cuspidatum, 8 parts of Epimedium, 8 parts of Eucommia, 5 parts of Guizhi, 5 parts of Safflower, and 5 parts of Sappan.
[0033] Preparation method: Take 4 traditional Chinese medicinal materials of Fangfeng, Duhuo, Epimedium, and Sappan, and cut them into 10-15mm sections. Mix it with the above 4 traditional Chinese medicinal materials, put it in a heat reflux extraction tank, add 5 times the amount of water to soak for 1 hour, heat reflux for 5 hours, concentrate to a specific gravity of 1.15-1.20, dry at 80 °...
experiment example 1
[0035] Process selection orthogonal experiment results are:
[0036] factor level table
[0037]
[0038] Orthogonal experiment design table and results
[0039]
[0040] The optimal experimental conditions selected from the above test results are: the extraction time of the medicinal materials is 5 hours, and the amount of the solvent is 5 times that of the medicinal materials.
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