19 results about "Caesalpinia sappan" patented technology

The application discloses a compound morinda officinalis color-increasing liniment for treating vitiligo and a preparation method thereof, and particularly relates to the technical field of traditional Chinese medicine preparations, wherein the liniment is prepared from morinda officinalis, spilanthes acmella, giant knotweed, caesalpinia sappan, psoralea corylifolia, radix angelicae dahuricae and rhizoma smilacis glabrae as raw medicinal materials. The preparation method comprises the following steps: dynamic reflux extraction, percolation extraction, macroporous adsorption resin purification and preparation molding. Through the classification extraction and purification process, the photosensitive active ingredients are retained, and the photo-toxic impurities are effectively removed, so that the photo-toxicity is completely negative. The pharmacodynamic test shows that the liniment has a significant curative effect on vitiligo. The safety test shows that the liniment has no skin irritation and no allergenicity, and has excellent light safety. The quality research shows that the quality of the liniment is stable and controllable. The liniment has definite curative effect, high safety and stable quality, and has a good clinical application prospect.

The application discloses a traditional Chinese medicine composition for treating lung cancer and a preparation method thereof. The traditional Chinese medicine composition comprises the following raw medicinal materials in parts by weight: Fritillaria thunbergii Miq. 5-8 parts, Caesalpinia sappan 5-8 parts, Polygonatum odoratum 5-8 parts, Iridaceae 5-8 parts, Platycodon grandiflorum 5-8 parts, Inula japonica 5-8 parts, Sasa veitchii 22-25 parts, Humulus scandens 9-12 parts, Bidens pilosa 22-25 parts and Glycyrrhiza uralensis 2-5 parts. The traditional Chinese medicine composition is developed on the basis of the phlegm and blood stasis blocking lung pathogenesis of lung cancer in traditional Chinese medicine diagnosis and treatment, combines the phlegm and blood stasis treatment method of traditional Chinese medicine and laboratory research, and has the effects of resolving phlegm and removing blood stasis and inhibiting tumor growth, and has a good effect on the treatment of lung cancer. Experiments prove that the traditional Chinese medicine composition significantly inhibits lung cancer cell proliferation in vitro experiments and improves the lung cancer pathological process of lung cancer mice in vivo experiments, and is a great innovation of a lung cancer treatment drug.

This invention discloses a medicinal mud for treating blood stasis and heat-induced arthralgia, its preparation method, and its application. The medicinal mud is composed of the following raw materials in parts by weight: 30-70 parts of *Hedyotis diffusa*, 30-70 parts of *Caesalpinia sappan*, 30-70 parts of *Gardenia jasminoides*, 30-70 parts of *Rheum palmatum* (processed with wine), 15-45 parts of *Stephania tetrandra*, 10-30 parts of *Sparganium stoloniferum*, 10-30 parts of *Curcuma zedoaria*, 10-30 parts of *Ligusticum chuanxiong*, 10-30 parts of *Smilax glabra*, 10-30 parts of *Geranium wilfordii*, 10-30 parts of *Polygonum cuspidatum*, 5-15 parts of *Cinnamomum cassia*, 5-15 parts of *Cyperus rotundus*, and 5-15 parts of *Citrus reticulata* (green tangerine peel). The above-mentioned treatment method scientifically combines a large number of heat-clearing, blood-cooling, and detoxifying herbs such as gardenia bark, rhubarb, Japanese knotweed, and smilax glabra with powerful blood-breaking and stasis-removing herbs such as sparganium rhizome, turmeric rhizome, sappanwood, and sclerotium tsao-ko. It is also supplemented with herbs that dispel dampness, unblock the meridians, promote qi circulation, and relieve pain. This method directly targets the three core elements of "blood stasis and heat arthralgia": "heat," "stasis," and "congestion." It treats internal diseases from the outside, with significant curative effects, and avoids the systemic toxic side effects of oral medications.

The invention relates to the technical field of pharmaceutical preparations, in particular to a myocardial protection traditional Chinese medicine composition capable of clearing heat, promoting blood circulation and removing blood stasis, a preparation and a preparation method and application of the myocardial protection traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following medicinal materials in parts by weight: 5-15 parts of gentiana acuminata, 10-20 parts of salvia miltiorrhiza, 5-15 parts of angelica sinensis, 10-20 parts of gynostemma pentaphylla, 5-15 parts of rhodiola rosea, 3-10 parts of hematoxylon, 5-15 parts of radix paeoniae rubra, 3-10 parts of lumbricus, 3-10 parts of radix curcumae, 10-20 parts of astragalus membranaceus, 3-10 parts of ginseng, 5-15 parts of radix ophiopogonis, 3-8 parts of schisandra chinensis and 3-8 parts of liquorice. According to the traditional Chinese medicine compound provided by the invention, through the synergistic effect of clearing heat, promoting blood circulation, removing blood stasis, tonifying qi and nourishing yin, the synergistic effect can be achieved more comprehensively aiming at the pathogenesis of heat-blood stasis intermingling. The traditional Chinese medicine composition has remarkable advantages in the aspect of treating myocardial ischemia reperfusion injury, the curative effect of the traditional Chinese medicine composition depends on complete monarch, minister, assistant and guide compatibility, and the overall medicine effect can be reduced if part of components are lost.

The invention discloses a traditional Chinese medicine composition for soothing channels and activating collaterals. The traditional Chinese medicine composition comprises the following components: 2-4 parts of asiatic toddalia root, 1-3 parts of raw pinellia ternate, 1-3 parts of monkshood, 1-3 parts of radix aconiti agrestis, 1-3 parts of radix aconiti carmichaeli, 3-5 parts of safflower, 3-5 parts of asarum, 3-5 parts of angelica sinensis, 3-5 parts of ligusticum wallichii, 1-3 parts of croton root, 3-5 parts of pepper, 3-5 parts of ground beeltle, 5-7 parts of pseudo-ginseng root, 3-5 parts of radix clematidis, 3-5 parts of sappan wood, 2-4 parts of cortex dictamni, 2-4 parts of radix angelicae pubescentis, 2-4 parts of honeycomb and 2-4 parts of frankincense. , 3-5 parts of pomegranate rind, 1-3 parts of hippocampus, 1-3 parts of centipede and 1-3 parts of dragon's blood. The traditional Chinese medicine composition for relaxing the channels and activating the collaterals has the effects of relaxing the channels and activating the collaterals, dispelling wind and eliminating dampness, and relieving swelling and pain, can effectively relieve swelling and pain caused by traumatic injury, blood stasis, joint dysfunction and the like, can be used for treating diseases such as traumatic injury, rheumatic arthralgia and the like after a fracture operation, also has a certain curative effect on stroke, is sprayed or smeared on an affected part, and has no toxic or side effect. A preservative film can be used for covering, so that the pesticide effect is greatly improved.

This invention discloses a compound moxa stick for warming yang and unblocking obstruction, its preparation method, and its application in improving reproductive system function. It belongs to the field of external preparations of traditional Chinese medicine. Addressing the problems of limited improvement effects of pure moxa sticks, lack of systematic design in compound moxa stick formulations, unclear synergistic effects between components, large fluctuations in conditioning effects, and difficulty in balancing conditioning effects and safety, this invention uses specific weight proportions of Artemisia argyi, Cyperus rotundus, Alpinia galanga, Cinnamomum cassia, Zingiber officinale, Illicium verum, Cinnamomum cassia twig, Spatholobus suberectus, Caesalpinia sappan, Smilax glabra, Euonymus fortunei, Citrus aurantium, Amomum villosum, Citrus reticulata peel, and Atractylodes lancea to prepare a compound moxa stick. The components synergistically enhance each other, and this product is used to prepare a moxibustion intervention product for improving the reproductive function of mammals. It can stably improve female ovarian reserve function and male asthenospermia, simultaneously regulate reproductive-related hormone levels, repair pathological damage to reproductive organs, and improve the quality of reproductive cells.

This invention discloses a traditional Chinese medicine composition for improving dark circles under the eyes and its application, belonging to the field of traditional Chinese medicine technology. Targeting the core pathogenesis of liver and kidney yin deficiency and qi stagnation and blood stasis, this invention, based on the theory of "principal, assistant, adjuvant, and guide" in traditional Chinese medicine formulation, uses *Artemisia capillaris* as the principal herb, peach kernel, *Corydalis yanhusuo*, and *Viola yedoensis* as assistant herbs, *Caesalpinia sappan*, *Notopterygium incisum*, *Kochia scoparia*, and turmeric as adjuvant herbs, and *Clematis chinensis* and *Lycopodium clavatum* as guide herbs to prepare a traditional Chinese medicine composition for improving dark circles under the eyes. This traditional Chinese medicine composition has the effects of promoting blood circulation and removing blood stasis, regulating qi and unblocking collaterals, clearing heat and cooling blood, reducing swelling and promoting diuresis. It can effectively improve the obstruction of collaterals around the eyes, tissue malnutrition, and water retention, thereby achieving the effect of lightening dark circles and improving the overall condition of the eye area.

This invention discloses a traditional Chinese medicine composition for reducing swelling and relieving pain, and its preparation method. The composition comprises the following medicinal ingredients: *Lycopodium clavatum*, *Clematis chinensis*, safflower, ephedra, *Pinus tabuliformis*, *Liquidambar formosana*, *Millettia speciosa*, *Tinospora sinensis*, *Caesalpinia sappan*, *Sparganium stoloniferum* (processed with vinegar), *Curcuma zedoaria*, and *Homalomena occulta*. All ingredients in this composition are natural Chinese herbal medicines, making the raw materials readily available, the preparation method simple, the cost low, and the use convenient. It can be mass-produced. This composition can effectively relieve symptoms of swelling and pain, improve the quality of life, and has high social value.

This is a traditional Chinese medicine fumigation and washing compound preparation for treating rheumatoid arthritis of the wind-cold obstruction type, belonging to the field of traditional Chinese medicine preparations for the treatment of rheumatoid arthritis. It is made from 10-25 parts of Morinda officinalis, 5-15 parts of Angelica sinensis (tail), 8-12 parts of raw licorice root, 5-12 parts of Schizonepeta tenuifolia, 5-15 parts of Atractylodes macrocephala, 8-15 parts of Clerodendrum trichotomum, 10-20 parts of Tripterygium wilfordii, 5-12 parts of Agkistrodon halys, 5-12 parts of Curcuma longa, 8-15 parts of Eucommia ulmoides powder, 8-15 parts of processed Strychnos nux-vomica, 8-15 parts of Caesalpinia sappan, and 5-15 parts of Cnidium monnieri. The traditional Chinese medicine fumigation and washing compound preparation proposed in this invention for treating rheumatoid arthritis of the wind-cold obstruction type is composed of Morinda officinalis, Angelica sinensis tail, raw licorice, Schizonepeta tenuifolia, Atractylodes macrocephala, Clerodendrum trichotomum, Tripterygium wilfordii, Agkistrodon halys, Curcuma longa, Eucommia ulmoides powder, processed Strychnos nux-vomica, Caesalpinia sappan, and Cnidium monnieri. Through heating, the effective components of the traditional Chinese medicine are extracted to achieve the effects of dispelling cold and dampness, and promoting blood circulation.

The invention relates to the technical field of preparation of health-care products, and provides a compound foot bath tablet as well as a preparation method and application thereof. The compound foot bath tablet comprises the following components: a monarch drug, a ministerial drug, an adjuvant drug, a conductant drug and auxiliary materials. Wherein the monarch drug comprises a rhodiola rosea extract, safflower, a lucid ganoderma extract, sea-buckthorn and crocus sativus salt; the ministerial drugs comprise fructus chebulae extract, fructus terminaliae billericae extract, emblic leafflower fruit extract, fructus schizandrae extract, radix codonopsis, radix salviae miltiorrhizae, herba leonuri, radix notoginseng, juniperus formosana, rhizoma kaempferiae extract, radix astragali seu hedysari, myricaria laxiflora, rhizoma chuanxiong, sea salt, herba artemisiae annuae, lavender and mirabilis jalapa extract; the adjuvant drugs comprise gentiana macrophylla extract, gentian extract, rhizoma bolbostemmae extract, divaricate saposhnikovia root, citrus peel, sappan wood, perilla leaf, herba lycopi extract, cowherb seed extract, tribulus terrestris, rhododendron and rheum palmatum; the conductant drug comprises gastrodia elata and calamus; the auxiliary materials comprise an effervescing agent, a disintegrating agent and an adhesive. The compound foot bath tablet can clear damp and help sleep, and is convenient to use, safe and reliable.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition and application and a preparation method thereof. The traditional Chinese medicine composition is mainly prepared from the following components in parts by weight: 3-35 parts of garden burnet, 2-22 parts of pawpaw, 2-18 parts of radix curcumae, 1-26 parts of radix stephaniae tetrandrae, 2-16 parts of rhizoma atractylodis, 3-13 parts of rhizoma bletillae, 5-23 parts of rhizoma corydalis, 2-20 parts of cortex phellodendri, 1-12 parts of borneol, 25-60 parts of calcined gypsum, 30-70 parts of calamine, 3-18 parts of frankincense, 2-15 parts of myrrh and 2-17 parts of dragon's blood. The traditional Chinese medicine is prepared from the following components in parts by weight: 2-16 parts of hematoxylon, 3-13 parts of rhizoma sparganii, 3-15 parts of notopterygium root, 2-16 parts of pseudo-ginseng and 85-150 parts of sesame oil. The traditional Chinese medicine composition disclosed by the invention is suitable for various long-term non-healing wounds with unknown reasons, such as long-term non-healing wounds caused by postoperative, infection, burn and diabetic foot, and sore and ulcer diseases such as chilblain, ecthyma, bedsore and the like, and has a remarkable curative effect.

The invention relates to three homoisoflavone compounds as well as a preparation method and application thereof. The compounds have structures as shown in compounds 1-3. The compound is separated from dry heartwood of sappan wood, has a new skeleton which is not disclosed in the prior art, and has neuroinflammation inhibition activity.

This invention provides a traditional Chinese medicine composition and foot bath pack for perioperative rehabilitation of uterine masses, belonging to the technical field of traditional Chinese medicine foot bath packs. The traditional Chinese medicine composition of this invention comprises the following raw materials by weight: 24-36 parts of Salvia miltiorrhiza, 24-36 parts of Spatholobus suberectus, 16-24 parts of Paeonia lactiflora, 16-24 parts of Caesalpinia sappan, 16-24 parts of Carthamus tinctorius, 12-18 parts of Prunus persica, 12-18 parts of Aconitum carmichaelii (processed), 16-24 parts of Artemisia argyi, and 16-24 parts of Achyranthes bidentata. The traditional Chinese medicine composition can be further processed into a foot bath pack. The traditional Chinese medicine composition and foot bath pack of this invention synergistically exert the effects of promoting blood circulation, removing blood stasis, warming the meridians, dispelling cold, and relieving pain. Applied to patients with uterine masses before and after surgery, it can significantly improve the preoperative blood circulation, relieve lower abdominal pain and distension, specifically regulate the preoperative pathological state of blood stasis, cold coagulation, and qi stagnation, improve surgical tolerance, and reduce the risk of postoperative complications.

The application provides an antitumor delphinine alkaloid in Caesalpinia minax, a core skeleton of angustifoline type, and provides an extraction method and application, and compound 3 is used for preparation of an antitumor drug. The natural delphinine with a new angustifoline type structural skeleton is obtained by separation and extraction, wherein compound 3 has a significant inhibitory effect on multiple tumor cell strains, and can be used for preparation of an antitumor drug.

This invention discloses the application of a traditional Chinese medicine composition in the preparation of drugs for the prevention and treatment of gastritis. The composition comprises the following ingredients: Astragalus membranaceus, ginseng, Atractylodes macrocephala, fermented Cordyceps militaris powder, Lycium barbarum, Hedyotis diffusa, Fagopyrum dibotrys, Bistorta officinalis, Panax notoginseng, and Caesalpinia sappan. This invention is the first to discover and confirm that this traditional Chinese medicine composition can be used to prevent or treat chronic gastritis, especially chronic atrophic gastritis. Experiments have verified that it can significantly prevent or improve the pathological state of the gastric mucosa in rats with chronic atrophic gastritis. Specifically, it can significantly increase the serum pepsinogen I / II ratio, decrease gastrin-17 levels, reverse gastric gland atrophy, and repair the morphological structure of the gastric mucosa, achieving a systematic repair of the function and structure of the CAG gastric mucosa. Furthermore, the ingredients in this traditional Chinese medicine composition are rationally combined, and no obvious toxic side effects were observed under experimental conditions, demonstrating good safety and potential for long-term use.

The invention discloses a dressing bag for dredging collaterals, relaxing tendons and ironing bones. Comprising phryma leptostachya, lycopodium clavatum, radix clematidis, caulis spatholobi, kadsura pepper stem, caulis sinomenii, Chinese starjasmine stem, photinia serrulata, tinospora sinensis merr, honeysuckle stem, ramulus mori, dryopteris pubescens, angelica sinensis, safflower, peach kernel, radix paeoniae rubra, hematoxylon, herba lycopi, artemisia anomala, prepared frankincense, prepared myrrh, pseudo-ginseng, ground beeltle, rhizoma bletillae, muskmelon seed, rhizoma drynariae, eucommia ulmoides, teasel root, radix cyathulae, cortex acanthopanacis, rhizoma cibotii, obscured homalomena rhizome, cassia twig, rhizoma zingiberis, folium artemisiae argyi, radix saposhnikoviae, notopterygium root and radix angelicae pubescentis. The preparation method comprises the following steps: decocting the medicinal materials except the borneol in the rice wine or yellow rice wine of 35-38 degrees, stirring and dissolving with the borneol to form a mixture, filtering the liquid in the mixture to obtain decoction dregs, packaging the decoction dregs to form the outer medicine bag, and heating the outer medicine bag to apply on the affected part firstly and then performing hot compress. According to the traditional Chinese medicine composition, the effects of warming and smoothing qi and blood are achieved, so that the effects of promoting blood circulation to remove blood stasis, relieving pain, promoting reunion of fractured tendons and bones, promoting tissue regeneration and meat growth and repairing soft tissues of the traditional Chinese medicine composition are accelerated.

The invention provides a hematoxylon hairy root genetic transformation system taking seeds as receptors, and belongs to the technical field of biology. The invention provides a hematoxylon seed-mediated genetic transformation method. The hematoxylon seed-mediated genetic transformation method comprises the following steps: stripping seed coats of hematoxylon seeds, and performing puncture treatment; mixing an infection solution containing a target gene with the hematoxylon seeds subjected to puncture treatment for infection; and planting the infected seeds to obtain the transgenic hematoxylon. The invention screens and verifies the unique advantages of the seeds as the hematoxylon genetic transformation receptor, establishes a hematoxylon genetic transformation system directly using the complete seeds as the receptor for the first time, and successfully bypasses the key bottleneck of the traditional technology. According to the genetic transformation method, the genetic transformation rate of hematoxylon is remarkably increased, and the genetic transformation rate is 15%; and the genetic transformation rate is stable, and the method has the advantages of high efficiency and repeatability.

This invention provides a traditional Chinese medicine composition for treating osteoporosis, including its calcium-supplementing and bone-strengthening properties, preparation method, and application. The composition comprises Dipsacus asper, oyster shell, Astragalus membranaceus, Angelica sinensis, Caesalpinia sappan, Curculigo orchioides, Drynaria fortunei, Eucommia ulmoides, Polygonum cuspidatum, and Glycyrrhiza uralensis. Through scientific and rational formulation and preparation methods, this traditional Chinese medicine composition exhibits the effects of invigorating qi and strengthening the spleen, tonifying the liver and kidneys, and supplementing calcium and strengthening bones, significantly improving the effectiveness of treating osteoporosis caused by calcium deficiency. Furthermore, this traditional Chinese medicine composition contains no toxic herbs, has few side effects, and is highly safe.

The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition capable of being combined with acupuncture to treat scapulohumeral periarthritis, a preparation and application of the traditional Chinese medicine composition. The composition is prepared from the following medicinal materials in parts by weight: 15 to 30 parts of rhizoma chuanxiong, 20 to 30 parts of rhizoma curcumae longae, 15 to 30 parts of peach kernel, 15 to 30 parts of flos carthami, 10 to 20 parts of pericarpium citri reticulatae viride processed with vinegar, 10 to 20 parts of rhizoma corydalis, 5 to 10 parts of radix aconiti lateralis preparata, 10 to 15 parts of cortex cinnamomi, 3 to 6 parts of herba asari, 20 to 30 parts of cortex erythrinae, 20 to 30 parts of herba siegesbeckiae, 15 to 25 parts of lignum sappan, 10 to 20 parts of semen brassicae, 15 to 25 parts of ramulus mori and 10 to 15 parts of radix glycyrrhizae. The invention provides a brand-new traditional Chinese medicine composition capable of treating scapulohumeral periarthritis by combining acupuncture, a preparation and application thereof, the traditional Chinese medicine composition is combined with acupuncture, and pain, stiffness and limited activity of scapulohumeral periarthritis can be synergistically improved by internally regulating qi and blood and externally dredging meridians and collaterals. A novel traditional Chinese medicine treatment thought is provided for clinical treatment of the scapulohumeral periarthritis disease.