Method for taking 3-aryl-5-methyl butyrolactone compound as acetylglucosyl bromide
An anti-plant virus agent, methyl butyrolactone technology, applied in botany equipment and methods, plant growth regulators, disinfectants, etc., can solve the problem that the inhibitory performance has not been seen in relevant reports, and achieve high bactericidal activity, Good bactericidal effect
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[0035] Example 1
[0036] A. The 3-aryl-5-methylbutyrolactone compound is a compound having a structure represented by the general formula (I) shown below:
[0037]
[0038] The compound of the structure shown in general formula (I) also includes I a And I b Two types, specific individual compounds are as follows:
[0039]
[0040]
[0041] B. The method of using the aforementioned 3-aryl-5-methylbutyrolactone compound as an anti-plant virus agent is as follows:
[0042] B-1. The steps for anti-tobacco mosaic virus activity are as follows:
[0043] The first step is the purification and concentration determination of tobacco mosaic virus:
[0044] Tobacco mosaic virus purification and concentration determination are carried out in accordance with the specifications of tobacco mosaic virus SOP compiled by the Bioassay Laboratory of the Institute of Elements, Nankai University. The crude virus extract is subjected to two polyethylene glycol centrifugation treatments, and the concentration ...
Example Embodiment
[0063] Example 2
[0064] In addition to the individual compound I of the above-mentioned 3-aryl-5-methylbutyrolactone compound in the second step a -1 In the preparation of the pharmaceutical solution, weigh the individual compound I of the above-mentioned 3-aryl-5-methylbutyrolactone compound a -140mg as the original drug, and then add 0.4mL of DMF to the original drug to dissolve it to obtain 1×10 5 μg / mL mother liquor, and then diluted with Tween 80 aqueous solution with a mass percentage concentration of 1‰ to a test concentration of 100 μg / mL, and the others are the same as in Example 1.
Example Embodiment
[0065] Example 3
[0066] The individual compounds other than the aforementioned 3-aryl-5-methylbutyrolactone compounds are I a -2, the others are the same as in Example 1.
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