Synthesis method of o-amino pheylmethyl ether

Abstract

The invention discloses a preparation method of o-amino pheylmethyl ether, and relates to the technical field of chemical industry. The method comprises the following steps: adding o-chloronitrobenzene, methanol and a 40-percent sodium hydroxide solution into a high-pressure reaction kettle in sequence, raising the temperature in the kettle to 40 DEG C, and stirring; raising the temperature to 85 DEG C, controlling the pressure at 0.28-0.32MPa, reacting for 8 hours, distilling, removing an internal methanol solution, adding hot water of 70 DEG C for washing, standing for delaminating, and performing liquid separation to obtain o-nitroanisole for later use; putting o-nitroanisole into the high-pressure reaction kettle, adding a sodium sulfide aqueous solution, controlling the pressure at 0.05MPa, controlling the temperature at 118-120 DEG C, pressurizing, refluxing, cooling to 50-60 DEG C, preserving heat for 5 hours, performing liquid separation, removing internal waste water, distilling, crystalizing, drying to obtain finished o-amino pheylmethyl ether, packaging and warehousing. The preparation method has the beneficial effects of convenience and easiness in preparation, environmental friendliness, pollution freeness, ready availability of raw materials, small equipment investment, high purity and convenience in operation. The prepared o-amino pheylmethyl ether has a good use effect, and is safe and reliable.

Description

technical field [0001] The invention relates to the technical field of chemical engineering, in particular to a synthesis method of anthranil. Background technique [0002] Anthranil, light red or light yellow oily liquid Uses: It can be used to prepare azo dyes, ice dyes, naphthol AS-OL and other dyes, as well as medicines such as guaiacol and anisotropy. It can also produce vanillin, etc. Anisole is a relatively expensive chemical substance with a relatively large demand in the market, and there are often situations in which the supply exceeds demand. Because it is used as a medical product, there are strict regulations on its purity. The traditional anisole production process is relatively complicated, and the purity of production is relatively low, which is difficult to meet the needs of human beings. Contents of the invention [0003] The technical problem to be solved by the present invention is to provide a method for preparing anthranilic ether with high purity an...

AI Technical Summary

Problems solved by technology

It can also produce vanillin, etc. Anisole is a relatively expensive chemical substance with a relatively large demand in the market, and there are often situations in which the supply exceeds demand. Because it is used as a medical product, there are strict regulations on its purity. The traditional anisole production process is relatively complicated, and the purity of the production is relatively low, which is difficult to meet the needs of human beings.