Extracts of microalgae and their application

A technology of extracts and microalgae, applied in hair care and skin care applications, the field of microalgae extracts, can solve the problem of no regulation of fat metabolism

Inactive Publication Date: 2014-10-15
CUTECH
View PDF11 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Japanese patent JP2000072642A1 (Lion) proposes weight loss preparations obtained from some species of macroalgae, however, there is no prior art available regarding fat metabolism regulation based on preparations obtained from the microalgae strains considered here
[0014] The state of the art is completely silent on the issues of regulation of the stratum corneum of the skin and lipolysis

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Extracts of microalgae and their application
  • Extracts of microalgae and their application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1 to 2

[0459] Activity of direct methanol (d-MeOH) extracted from Chaetoceros sp. on hair follicle growth

[0460] Hair follicles were taken from scalp samples of individual donors and transferred to sterile 24-well plates for culture by using modified Williams' Medium E. The culture was carried out for ten days, while the experimental treatment of the hair follicles was carried out for 24 hours from the beginning of the culture. Hair follicles for experiments were selected after 18 hours of incubation. Only those hair follicles showing a good state of life and growing no less than 0.2 mm were considered suitable for culture. All experimental and control groups were prepared including 12 hair follicles, which were seeded in 24-well plates at a density of 3 hair follicles / well. Follicles showing obvious signs of tolerance during culture due to non-experimental treatments were excluded from the final analysis. In the case of direct methanolic extract (d-MeOH) obtained from dried bio...

Embodiment 3 to 4

[0466] Activity of direct ethanol (d-EtOH) extract obtained from Chaetoceros dwarfism on hair follicle growth

[0467] A previously described experimental protocol was employed to investigate the activity of direct ethanol extracts obtained from Chaetoceros dwarfism on hair follicle growth. Experiments were repeated twice using follicles from two donors. The reported results were calculated by pooling the recorded data and are shown in Table 3.

[0468] table 3

[0469] Growth-elongation of hair follicles is expressed as a % ratio of the performance of the control group. Pooled data from two of the two tested donors (response = 100%)

[0470] Example

[0471] Direct ethanol extracts stimulated hair follicle growth, inducing increases in elongation varying from 17% to 20%. Both results were statistically significant, however, the best response was detected by treating the follicles with 1 μg / ml of the extract.

Embodiment 5 to 6

[0473] Activity of direct isopropyl (d-iPrOH) alcoholic extracts obtained from Chaetoceros sp. on hair follicle growth

[0474] A previously described experimental protocol was employed to investigate the activity of direct isopropyl alcohol extracts obtained from Chaetoceros sp. on the growth of hair follicles. In Table 4, the results of individual experiments are reported.

[0475] Table 4

[0476] Growth-elongation of hair follicles is expressed as a % ratio of the performance of the control group. (data from a single experiment)

[0477] Example

[0478] Direct isopropanol extracts inhibited hair follicle growth, resulting in reductions in elongation ranging from -24% to -31%. The best response was detected by treating the follicles with the extract at 10 μg / ml and this result was very statistically significant.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
diameteraaaaaaaaaa
diameteraaaaaaaaaa
Login to view more

Abstract

Suggested are new extracts of microalgae selected from the group consisting of (i) Monodus sp. (ii) Thalassiosira sp. (iii) Chaetoceros sp. and/or (iv) Chlorococcum sp. obtainable by treating said microalgae with a solvent selected from the group consisting of C1-C4 aliphatic alcohols, ethyl acetate, water or their mixtures, removing the dissolved extracts from the residues and recovering the pure extracts from the solvent. The extracts show excellent properties particularly in modulating the metabolism of human skin and hair follicles.

Description

technical field [0001] The present invention relates to the field of cosmetics and toiletries and relates to extracts of microalgae, methods and compositions for obtaining the extracts, and their use in hair care and skin care applications. Background technique [0002] The cosmetic and toiletries industry has invested a great deal of interest in identifying natural compounds suitable for use in the preparation of body care products, especially those with an anti-aging focus. Declining birth rates and increasing longevity experienced in industrialized economies has increased the impact of anti-aging products in the nutraceutical and cosmetics market. [0003] Wrinkles represent one of the more visible symptoms of skin aging and cosmetics have been working on this problem for many years. Decreased and structurally altered dermal collagen is believed to be the main cause of skin wrinkles. Collagen stimulators have been actively screened among synthetic compounds and natural ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/97A61Q5/00A61Q7/00A61Q7/02A61Q19/00A61Q19/02A61Q19/04A61Q19/08
CPCA61Q5/00A61Q7/02A61K8/975A61K8/99A61Q19/00A61K36/02A61Q19/02A61Q19/08A61Q7/00A61Q19/04A61K8/97A61Q19/06A61K8/34A61K8/37A61P17/02A61K8/9722A61K8/9794A61K8/9706
Inventor 洛伦佐·扎内拉保罗·佩尔蒂莱米歇尔·马西罗尼马科·马西罗尼埃里萨·卡维奥拉
Owner CUTECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap