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Application of irpex lacteus in preparing anti-hypoxia medicaments

A technology of Racula albicans and hypoxia resistance, which is applied in the field of medicine, can solve the problems of different types of Racula albicans, achieve the effects of small toxic and side effects, simple preparation method, and low cost

Active Publication Date: 2014-11-12
JILIN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the efficacy of the same species of P. albicans is completely different due to the different growth environment.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Embodiment 1: the preparation of the extract of Racula albicans

[0015] The fermented liquid was obtained by fermenting the fungus albicans, centrifuged at 4000 rpm for 10 minutes, the supernatant was discarded, and the precipitate was freeze-dried to obtain the fungus powder, which was then extracted with deionized water for 2 The second time, according to the liquid-to-material ratio of 1:40, the temperature is 90 ° C, the first time is 3 hours, the second time is 1 hour, the two water extracts are combined, and the filtrate is obtained with a 200 mesh filter cloth, and the filtrate is concentrated. Add ethanol until the alcohol concentration is 80%, stir overnight, filter and take the precipitate, and freeze-dry the precipitate to obtain the extract of R. albicans.

Embodiment 2

[0017] The fermented liquid was obtained by fermenting the fungus albicans, centrifuged at 4500 rpm for 8 minutes, the supernatant was discarded, and the precipitate was freeze-dried to obtain the fungus powder of the fungus. The material ratio is 1:40, the temperature is 80°C, the first time is 3 hours, the second time is 1 hour, the two water extracts are combined, and the filtrate is obtained with a 200-mesh filter cloth, the filtrate is concentrated, and then ethanol is added to ethanol. The concentration is 80%, stir overnight, filter and take the precipitate, and freeze-dry the precipitate to obtain the extract of R. albicans.

Embodiment 3

[0019] Get the fermented liquid from the fungus A. albicans through a fermenter, centrifuge it at 5000 rpm for 5 minutes, discard the supernatant, and freeze-dry the precipitate to obtain the powder of the fungus, then extract the powder twice with water, press the liquid The material ratio is 1:40, the temperature is 70°C, the first time is 3 hours, the second time is 1 hour, the two water extracts are combined, and the filtrate is obtained with a 200-mesh filter cloth, the filtrate is concentrated, and then ethanol is added to ethanol. The concentration is 80%, stir overnight, filter and take the precipitate, and freeze-dry the precipitate to obtain the extract of R. albicans.

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PUM

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Abstract

The invention provides application of irpex lacteus in preparing anti-hypoxia healthy products. The irpex lacteus is prepared by fermentation, water extraction, alcohol sedimentation and lyophilizing methods. Animal experiments prove that the irpex lacteus has a remarkable anti-hypoxia effect. The irpex lacteus has the advantages of simple preparation method, low cost, small toxic and side effect and remarkable anti-hypoxia effect, and is suitable for preparation of anti-hypoxia healthy foods or medicinal preparations.

Description

technical field [0001] The invention relates to the technical field of medicines, in particular to the use of R. albicans in the preparation of hypoxia-resistant medicines. Background technique [0002] Oxygen is necessary for the existence of most life forms. After people living in the plains enter the plateau, the lack of oxygen has a great impact on human body functions, resulting in a decline in labor capacity. The higher the altitude, the more obvious the decline in labor capacity. [0003] Hypoxia widely exists in human life and work. It involves medicine, sports, military and other fields. It is also the pathological basis for the occurrence and development of many diseases. The brain and heart muscle are very sensitive to hypoxia. Generally, short-term or mild hypoxia can cause rapid heartbeat, purple lips, dizziness, headache, and may even cause symptoms such as vomiting, diarrhea, shortness of breath, and coma; prolonged or severe hypoxia can cause insufficient en...

Claims

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Application Information

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IPC IPC(8): A61K36/07A61P39/00A23L1/28A23L2/52
Inventor 王迪李臣亮滕利荣孟庆繁宋佳逯家辉刘艳王贞佐周毓麟刘春刚程瑛琨权宇彤
Owner JILIN UNIV
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