A traditional Chinese medicine compound for treating angina pectoris with diffuse coronary disease

A technology of traditional Chinese medicine and venereal disease, which is applied in the field of traditional Chinese medicine compound prescriptions for the treatment of angina pectoris with diffuse coronary lesions, and achieves the effects of improvement and disease progression, improvement of cardiac function and quality of life, and definite curative effect.

Active Publication Date: 2018-06-05
THE AFFILIATED HOSPITAL OF SHANDONG UNIV OF TCM
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Purpose of the present invention: mainly aiming at patients with diffuse coronary artery disease who cannot perform PCI or CABG coronary revascularization in clinical practice, by exploring its pathogenesis, invent a Chinese medicine compound for treating angina pectoris with diffuse coronary artery disease, And achieved good curative effect, providing a new method for solving this clinical problem

Method used

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  • A traditional Chinese medicine compound for treating angina pectoris with diffuse coronary disease
  • A traditional Chinese medicine compound for treating angina pectoris with diffuse coronary disease
  • A traditional Chinese medicine compound for treating angina pectoris with diffuse coronary disease

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Embodiment 1

[0070] Gao, male, 56 years old, was hospitalized in a local hospital for chest pain and distress in 2010. Coronary CT showed diffuse calcification of the coronary arteries and diffuse stenosis of the three main coronary arteries. Diagnosed with coronary heart disease, conservative medical treatment, anti-platelet, expansion of coronary vessels, blood lipid regulation and other symptomatic treatment, improved and discharged. The patient had hypertension for 8 years in the past, and the blood pressure was 160 / 90mmHg, which was not taken seriously. Patients usually take Betaloc Sustained-release Tablets orally intermittently to control heart rate and reduce myocardial oxygen consumption, antihypertensive drugs such as Lodinsin and Diovan to control blood pressure, aspirin to resist platelets, and Lyme can regulate blood lipids and delay the progression of arterial plaques.

[0071] First visit on September 4, 2012: The patient recently developed chest pain, chest tightness, and s...

Embodiment ２

[0082] Zhang, female, 62 years old, was treated in a local hospital for chest pain and distress in 2006. She was diagnosed with coronary heart disease. Coronary CT showed diffuse calcification and diffuse stenosis of the coronary artery, and the left main artery stenosis was >50%. The patient had a history of hypertension for 10 years, the highest blood pressure was 180 / 100mmHg, and diabetes for 3 years. The patient usually takes Betaloc orally to control heart rate, Baixintong and Diovan to control blood pressure, metformin to regulate blood sugar, and aspirin to prevent platelet aggregation, and the condition is well controlled.

[0083] First consultation on September 27, 2012

[0084] The patient has recently developed chest tightness and chest pain without any obvious cause, which can also occur during rest, accompanied by shortness of breath, fatigue, dizziness, occasional cough, abdominal distension, good appetite, lack of sleep, easy to wake up, normal urination, dry s...

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Abstract

The present invention is a traditional Chinese medicine compound for treating angina pectoris caused by diffuse coronary disease, which comprises the raw materials of the following components by weight: Astragalus 15-45g, Ophiopogon japonicus 10-30g, Rhizoma Chuanxiong 9-15g, Hirudo 6-9g, Pueraria mirifica 15g ~30g, Forsythia 9~18g, Coptidis 9~15g, Gardenia 6~18g, Guizhi 9~27g, Radix Paeoniae Alba 9~27g, Licorice 6~12g; any one or more of the following raw materials can be included Combination: Schisandra 6-15g, Scutellaria baicalensis 6-15g, Yuanhu 10-30g, Panax notoginseng powder 2-6g and Codonopsis 12-30g. For the treatment of diffuse coronary lesions, it can clearly show the myocardial ischemia and angina symptoms of patients, and solve the embarrassing problem that current clinical western medicine cannot perform coronary blood flow reconstruction for this disease. The treatment method is simple and easy, and there is no adverse reaction. The curative effect is exact.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and relates to a traditional Chinese medicine compound for treating angina pectoris with diffuse coronary disease. Background technique [0002] Diffuse coronary artery disease means that the length of coronary artery stenosis is greater than 20mm. It is one of the complex types of coronary artery disease. Patients will experience angina pectoris and decreased cardiac function. Percutaneous coronary intervention (PCI) is difficult and intraoperative complications The incidence rate is high, and its restenosis rate is high after PCI, and it is also an independent risk factor for restenosis after PCI. Diffuse lesions at the distal end of stenosis or too small diameter will limit the blood flow of the grafted vessels and the distal end of the anastomosis after coronary artery bypass grafting (CABG), leading to the occurrence of adverse cardiac events. The reason is that percutaneous cor...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8968A61P9/10A61K35/62
Inventor 李晓丁书文姜萍
Owner THE AFFILIATED HOSPITAL OF SHANDONG UNIV OF TCM
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