Paddle and disc positioned sedimentation equilibrium device

A sedimentation balance and positioning device technology, which is applied to mixers with rotating stirring devices, mixers, dissolution, etc., can solve the problems of the third method that does not consider the release degree, and the difficulty of horizontally balanced placement of net dishes, so as to avoid naked eye observation and manual adjustment and error, ensure horizontal placement, convenient and accurate operation

Active Publication Date: 2014-11-19
广州法尔麦兰药物技术有限公司 +1
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Ordinary dissolution apparatus is not designed for the third method of dissolution. The position of the stirring paddles in the dissolution vessel is different between the pad

Method used

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  • Paddle and disc positioned sedimentation equilibrium device
  • Paddle and disc positioned sedimentation equilibrium device
  • Paddle and disc positioned sedimentation equilibrium device

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Embodiment 1

[0017] Such as figure 1 , 2 , 3, the paddle-disc positioning settlement balance device of the present invention includes a dissolution vessel 6, a stirring paddle 8, a net dish 7, a positioning component 5, and also includes a positioning device 4 and an auxiliary horizontal balance placement device 3. The positioning device 4 is a three-dimensional structural component that can be stably placed above the positioning component 5; the auxiliary horizontal balance placement device 3 includes an upper part 1 and a lower part 2, and the lower part 2 of the auxiliary horizontal balance placement device 3 is located in the dissolution vessel 6.

[0018] The positioning device 4 is a cylinder or a cuboid made of a material with appropriate hardness, preferably stainless steel or aluminum alloy.

[0019] The upper part 1 is a flat plate structure, and the lower part 2 is a cylinder, which is made of a material that is rigid and does not react with drugs, preferably organic glass or p...

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PUM

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Abstract

The invention discloses a paddle and disc positioned sedimentation equilibrium device. The paddle and disc positioned sedimentation equilibrium device comprises a dissolving cup, a stirring paddle, a net disc and a positioning component and is characterized by also comprising a positioning device and an auxiliary horizontal balancing device, wherein the positioning device is a three-dimensional structure component which is stably placed on the positioning component; the auxiliary horizontal balancing device comprises an upper component and a lower component, and the lower component of the auxiliary horizontal balancing device is positioned in the dissolving cup. According to the invention, an existing dissolution rate determination instrument, which conforms to a dissolution rate determination method (namely a paddle method) in an appendix XC of Chinese pharmacopoeia II (2010 edition), can meet the requirement on the distance from the bottom of a stirring paddle to a patch in a third release determination method (for a transdermal patch) in the appendix of Chinese pharmacopoeia, and the paddle and disc positioned sedimentation equilibrium device is convenient and accurate to operate, prevents errors of observation by eyes and manual regulation, and guarantees that the net disc is placed horizontally.

Description

Technical field: [0001] The invention relates to a drug dissolution device, in particular to a paddle-disk positioning and sedimentation balance device. Background technique: [0002] Chinese Pharmacopoeia 2010 Edition Appendix XD The third method of release test method (used for transdermal patch) mainly adopts the second method of dissolution test method (paddle method), the stirring paddle, the dissolution cup, and another network dish. Paddle disc device. Ordinary dissolution apparatus is not designed for the third method of dissolution. The position of the stirring paddles in the dissolution vessel is different between the paddle-disc device and the second method of dissolution (paddle method), and the mesh disc is used in actual operation. Difficult to balance horizontally in a dissolution vessel. Invention content: [0003] The purpose of the present invention is to provide a paddle plate positioning settlement balance device for adjusting the height of the positi...

Claims

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Application Information

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IPC IPC(8): B01F7/18B01F15/00B01F1/00G01N33/15
Inventor 池舒耀张怡孙晋红张小明丁艺钊黄小棠蒋志军
Owner 广州法尔麦兰药物技术有限公司
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