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A new application of traditional Chinese medicine composition

A composition and technology of traditional Chinese medicine, applied in the field of medicine, can solve problems such as long course of treatment

Active Publication Date: 2017-12-29
郑州市新视明科技工程有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But the treatment course of this group is obviously longer

Method used

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  • A new application of traditional Chinese medicine composition
  • A new application of traditional Chinese medicine composition
  • A new application of traditional Chinese medicine composition

Examples

Experimental program
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Effect test

Embodiment 1

[0128] [Prescription] 500g medlar, 500g chrysanthemum, 333g salvia, 500g cork, 16.7g pearl powder, 0.5g borneol, 1.0g menthol;

[0129] [Preparation method] Take the above seven herbs, take wolfberry, chrysanthemum, salvia miltiorrhiza, and Phellodendron phellodendri, add 12 times of water to decoct twice, each time for 1.5 hours, filter, concentrate the filtrate to a relative density of 1.05-1.10 (40°C), and cool to room temperature , add an appropriate amount of ethanol to make the alcohol content reach 50%, refrigerate and stand at 4°C for 12 hours, filter, recover the ethanol to get the extract extract, and set aside; take pearl powder, add 25% lactic acid, stir well, and stir every half an hour Once, heat and hydrolyze twice at 65°C, each time for 3 hours, filter, and the filtrate is pearl hydrolyzate for later use; use beta cyclodextrin for borneol and menthol (borneol, menthol: β-CD=1:8, β- CD (g): water (ml) = 1:10, use a colloid mill to grind for 15 minutes) for inclu...

Embodiment 2

[0131] 600g medlar, 500g chrysanthemum, 400g salvia, 520g cork, 20g pearl powder, 0.2g borneol, 6g menthol;

[0132] For the above seven herbs, take medlar, chrysanthemum, salvia miltiorrhiza, Phellodendron phellodendron and add 50% ethanol to reflux extract 3 times, each time for 1.5h, filter, combine the extracts, reclaim the ethanol to obtain the extract extract, and set aside; pearl powder hydrolyzate and package The preparation of the compound is the same as in Example 1; the above extract extract is mixed with pearl hydrolyzate and beta-cyclodextrin inclusion compound, and coated on a non-woven fabric to make an eye patch.

Embodiment 3

[0134] 540g medlar, 600g chrysanthemum, 310g salvia, 580g cork, 16g pearl powder, 4g borneol, 0.6g menthol;

[0135] For the above seven herbs, take medlar, chrysanthemum, salvia miltiorrhiza, Phellodendron phellodendri and 70% ethanol and ultrasonically extract 3 times, each time for 40 minutes, combine the extracts, filter, concentrate the filtrate, centrifuge at 3000r / min for 15 minutes, take the supernatant, and concentrate it into Extraction, for subsequent use; the preparation of pearl powder hydrolyzate and inclusion compound is the same as in Example 1; the above extract is mixed with pearl hydrolyzate and beta-cyclodextrin inclusion compound, and coated on non-woven fabric to make eye paste.

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Abstract

The invention provides a new application of a traditional Chinese medicinal composition and in particular relates to an application of a traditional Chinese medicinal composition in preparation of a medicine used for treating xerophthalmia, and raw materials of the traditional Chinese medicinal composition comprise wolfberry, chrysanthemum, salviae miltiorrhizae, cortex phellodendri, borneol, pearl powder and menthol. The traditional Chinese medicinal composition has the advantages that pathological changes of lacrimal gland tissues of an experimental xerophthalmia mouse, lacrimal glands of which are damaged by injected pingyangmycin, in morphology can be obviously alleviated, quantity of tear fluid can be obviously increased, breakup time of a tear film is prolonged, and quantity of the tear fluid secreted by a normal domestic rabbit can be obviously increased; and meanwhile, the traditional Chinese medicinal composition has obvious anti-inflammation and anti-oxidation effects.

Description

technical field [0001] The invention relates to a new application of a traditional Chinese medicine composition, in particular to a new application of a traditional Chinese medicine composition in the preparation and treatment of dry eye, and belongs to the field of medicine. Background technique [0002] Dry eye syndrome, also known as Xerophthalmia, is a multifactorial disease of the tear fluid and ocular surface, including symptoms of ocular surface discomfort, vision changes, and tear film instability with potential Ocular surface damage, accompanied by increased tear osmolarity and ocular surface inflammation. Common symptoms are: dryness, foreign body sensation, burning sensation, itching, photophobia, red eyes, blurred vision, vision fluctuations, etc. Severe dry eye can cause significant loss of vision, which affects their normal work and life, and even leads to blindness. The current conventional method for treating dry eye is to drop eye drops with lubricating fu...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/815A61P27/02A61P29/00A61P39/06A61P9/04A61K31/045A61K35/618
CPCA61K9/0048A61K9/06A61K9/7023A61K31/045A61K35/618A61K36/287A61K36/537A61K36/756A61K36/815A61K2236/33A61K2236/331A61K2236/53A61K2300/00
Inventor 张晓娟
Owner 郑州市新视明科技工程有限公司
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