Chinese herbal medicine composition for removing freckles as well as preparation method and application of Chinese herbal medicine composition
A Chinese herbal medicine composition and the technology of the composition, which are applied in the directions of drug combinations, pharmaceutical formulations, cosmetic preparations, etc., can solve the problems of unsatisfactory freckle removal effect, skin allergy, recurrence and aggravation of pigmentation, etc., and achieve stable curative effect, remove freckles, and effectively freckles effect
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Embodiment 1
[0071] Embodiment 1 Preparation of freckle-removing Chinese herbal medicine composition of the present invention
[0072] Take each bulk drug according to the following proportions by weight:
[0073] Dandelion 41kg; Artemisia chinensis 31kg; Ginseng palm 20kg; Meconopsis prickly 13kg.
[0074] (1) Crushing and mixing the raw materials through a 40-mesh sieve;
[0075] (2) adding 80% ethanol for cold soaking and ultrasonic extraction, the mass ratio of crude drug to ethanol is 1:10, the immersion time at room temperature is 1 hour, and the ultrasonic extraction time is 40 minutes;
[0076] (3) Filtrate, and add 80% ethanol with a mass ratio of 1:5 to the remaining residue for ultrasonic extraction for 20 minutes;
[0077] (4) Filtrate, combine the extracts obtained twice, and concentrate under reduced pressure to obtain the active extract.
Embodiment 2
[0078] Embodiment 2 The preparation of the freckle-removing Chinese herbal medicine composition of the present invention
[0079] Take each bulk drug according to the following proportions by weight:
[0080] Dandelion 22kg; Artemisia chinensis 19kg; Ginseng palm 16kg; Meconopsis prickly 10kg.
[0081] (1) Crushing and mixing the raw materials through a 30-mesh sieve;
[0082] (2) adding 80% ethanol cold immersion ultrasonic extraction, the mass ratio of crude drug and ethanol is 1:9, the soaking time at room temperature is 40 minutes, and the ultrasonic extraction time is 50 minutes;
[0083] (3) Filtrate and concentrate under reduced pressure to obtain the active extract.
Embodiment 3
[0084] Embodiment 3 Preparation of freckle-removing Chinese herbal medicine composition of the present invention
[0085] Take each bulk drug according to the following proportions by weight:
[0086] Dandelion 46kg; Artemisia chinensis 36kg; Ginseng palm 26kg; Meconopsis prickly 16kg.
[0087] (1) Crushing and mixing the raw materials through a 40-mesh sieve;
[0088] (2) adding 80% ethanol for cold soaking and ultrasonic extraction, the mass ratio of bulk drug to ethanol is 1:12, the immersion time at room temperature is 1 hour, and the ultrasonic extraction time is 40 minutes;
[0089] (3) Filtrate, and add 80% ethanol with a mass ratio of 1:6 to the remaining residue for ultrasonic extraction for 20 minutes;
[0090] (4) Filtrate, combine the extracts obtained twice, and concentrate under reduced pressure to obtain the active extract.
[0091] The evaluation of the safety of the freckle-removing Chinese herbal medicine composition of the present invention and the freckl...
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