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Saponin extract of tremella aurantialba fruiting body as well as preparation method and application thereof

A technology of golden ear fruiting body and extract, applied in the direction of drug combination, pharmaceutical formula, plant raw material, etc., to achieve the effect of enhancing curative effect, increasing the ability to phagocytose chicken red blood cells, and enhancing body immunity

Active Publication Date: 2015-03-04
BEIJING LYUKE TIANCHENG BIO TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Saponins are a class of active substances with a variety of physiological functions, but there is no literature or patent report on the composition of saponins in the fruiting body of Auricularia auricosa.

Method used

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  • Saponin extract of tremella aurantialba fruiting body as well as preparation method and application thereof
  • Saponin extract of tremella aurantialba fruiting body as well as preparation method and application thereof
  • Saponin extract of tremella aurantialba fruiting body as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0063] Example 1 Tremella saponins extract

[0064] Golden ear fruit body saponin extract, with ginsenoside R b1 It is calculated that the saponin extract contains 60% total saponin, and the saponin extract is prepared by the following method:

[0065] (1) Crush the golden ear fruit bodies, pass through a 40-mesh sieve, and set aside;

[0066] (2) Add petroleum ether to the pulverized golden ear fruit body at a solid-liquid ratio of 1:80, and extract 5 times at a temperature of 80°C for 6 hours each time; let stand to remove the petroleum ether, and collect the residue after petroleum ether extraction , Air dried;

[0067] (3) Add water with a solid-to-liquid ratio of 1:80 to the residue after petroleum ether extraction, extract 5 times at 100°C, 4 hours each time, combine the extracts, filter with suction, dry the filter cake, and collect the water after extraction Residue

[0068] (4) Add 30% ethanol to the residue after water extraction at a solid-liquid ratio of 1:80, and extract ...

Embodiment 2

[0071] Example 2 Tremella fruit body saponin extract

[0072] Golden ear fruit body saponin extract, with ginsenoside R b1 It is calculated that the saponin extract contains 53% total saponin, and the saponin extract is prepared by the following method:

[0073] (1) Crush the golden ear fruit bodies, pass through a 20-mesh sieve, and set aside;

[0074] (2) Add petroleum ether to the crushed golden ear fruit body at a solid-liquid ratio of 1:60, and extract 5 times at a temperature of 75°C for 8 hours each time; let stand to remove the petroleum ether, and collect the residue after petroleum ether extraction , Air dried;

[0075] (3) Add water with a solid-to-liquid ratio of 1:60 to the residue after petroleum ether extraction, extract twice at 90°C for 5 hours each time, combine the extracts, filter with suction, dry the filter cake, and collect the water after extraction Residue

[0076] (4) Add 50% ethanol to the residue after water extraction according to a solid-liquid ratio of 1...

Embodiment 3

[0080] Example 3 Tremella saponins extract

[0081] Golden ear fruit body saponin extract, with ginsenoside R b1 It is calculated that the saponin extract contains 48% total saponin, and the saponin extract is prepared by the following method:

[0082] (1) Crush the golden ear fruit bodies, pass through a 30-mesh sieve, and set aside;

[0083] (2) Add petroleum ether to the crushed golden ear fruit body at a solid-liquid ratio of 1:40, and extract 3 times at a temperature of 70°C for 5 hours each; let stand to remove the petroleum ether and collect the residue after petroleum ether extraction. , Air dried;

[0084] (3) Add water with a solid-to-liquid ratio of 1:40 to the residue after petroleum ether extraction, extract 4 times at 70°C, 2h each time, combine the extracts, filter with suction, dry the filter cake, and collect the water after extraction Residue

[0085] (4) Add 40% ethanol to the residue after water extraction at a solid-liquid ratio of 1:40, and extract 3 times at a t...

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Abstract

The invention relates to a saponin extract of a tremella aurantialba fruiting body as well as a preparation method and an application thereof. The saponin extract contains 20-60 percent of total saponins based on calculation of panaxoside Rb1. The extract is prepared by the following methods: extracting by using a low-polarity organic solvent so as to remove liposoluble substances in the tremella aurantialba fruiting body; performing water extraction to remove water-soluble substances; extracting and concentrating by using 30-70 percent of ethanol liquid; and re-dissolving by using ethanol, and precipitating to obtain the saponin extract of tremella aurantialba fruiting body. The saponin extract provided by the invention has the effects of reducing blood sugar, regulating blood fat and enhancing the body immunity, a brand-new way is developed for deep development and utilization of tremella aurantialba, and ideal medicines are provided for reducing the blood sugar, regulating the blood fat and enhancing the body immunity.

Description

Technical field [0001] The invention relates to an extract, in particular to a golden ear fruit body saponin extract and a preparation method and application thereof. Background technique [0002] Diabetes and hyperlipidemia are common and frequently-occurring diseases of middle-aged and elderly people at present. Complications caused by diabetes and hyperlipidemia seriously endanger people's lives and health. Existing western medicine hypoglycemic drugs inevitably have side effects, and natural Chinese medicine hypoglycemic drugs are favored by people. [0003] Golden fungus, named after its fruit body is golden yellow, also known as golden fungus, yellow fungus, golden fungus, yellow ear, brain ear, glue ear, the fungus belongs to the fungus phylum, Basidiomycetes (Basidiomycetes). ), Tremellales, Tremellaceae, Tremella, the scientific name Tremella aurantialbavb; mainly distributed in the Yunnan-Guizhou Plateau in my country, it is a kind of precious edible and medicinal fungus,...

Claims

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Application Information

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IPC IPC(8): A61K36/06A61P3/10A61P3/06A61P37/04
CPCA61K9/2054A61K36/07A61K36/28A61K36/30A61K36/39A61K36/42A61K36/704A61K36/73A61K2236/331A61K2236/333A61K2236/35A61K2236/53A61K2300/00
Inventor 王永生
Owner BEIJING LYUKE TIANCHENG BIO TECH
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