Postoperative anti-adhesion medical dressing and preparation method thereof

Abstract

The invention relates to postoperative anti-adhesion medical dressing and a preparation method thereof, belonging to the field of biological materials. The postoperative anti-adhesion medical dressing comprises medical non-woven fabric, wherein a layer of chitosan is arranged on the surface of the medical non-woven fabric; the chitosan is fixed on the medical non-woven fabric through a cross-linking agent; a layer of hyaluronic acid hydrogel is arranged on the chitosan; the chitosan and the hyaluronic acid hydrogel are fixed through an ionic bond between the chitosan and the hyaluronic acid hydrogel. The postoperative anti-adhesion medical dressing disclosed by the invention has a good postoperative anti-adhesion effect, so that the intensity of the dressing is increased; the chitosan is used as an adhesion layer with bacteriostatic activity, so that the wound infection is effectively prevented. The invention further provides a preparation method for the postoperative anti-adhesion medical dressing. The adopted raw materials are biodegradable natural high polymer materials, the biocompatibility is good, the method is simple, the used solvent is water, and organic solvent residue is avoided.

Description

technical field [0001] The invention relates to a postoperative anti-adhesion medical dressing and a preparation method thereof, in particular to a postoperative anti-adhesion medical dressing containing hyaluronic acid hydrogel, which belongs to the field of biological materials. Background technique [0002] Medical dressings are a kind of medical materials used for temporary covering of various wounds and wound surfaces, which can protect the wounds from bacterial infection and other external factors, and protect the wounds and wound surfaces. Traditional dressings mainly use padding, gauze, interlining or similar coverings to protect wounds and wound surfaces, and have played an important role in the field of medical and health care. But its effect is not very satisfactory, mainly reflected in that these traditional dressings are easy to dry after absorbing liquid, and are easy to adhere to the wound to cause secondary trauma, causing damage to the new tissue when it is ...

AI Technical Summary

Problems solved by technology

[0004] The technical problem to be solved by the present invention is: in order to solve the problems that the traditional dressings in the prior art are easy to stick, have poor strength, and are prone to wound infection, the present invention provides a postoperative anti-adhesion medical dressing, which adopts chitosan layer The connection and fixation of medical non-woven fabric and hyaluronic acid hydrogel has good postoperative anti-adhesion effect, and the chitosan layer is cleverly used to connect hyaluronic acid hydrogel and medical non-woven fabric, increasing the dressing strength, using chitosan as the bonding layer has antibacterial activity and effectively prevents wound infection; the invention provides a preparation method of postoperative anti-adhesion medical dressing, and the raw material used is biodegradable natural high Molecular material with good biocompatibility, simple method, and the solvent used is water, no organic solvent residue