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Application of Artemisia carvifolia in preparation of gastrointestinal disease treatment drugs

A technology for gastrointestinal diseases and Artemisia annua, applied in the field of pharmaceuticals, can solve the problems of contradicting the principle of clinical rational use of antibiotics, high treatment costs, and many adverse reactions, so as to reduce the economic burden of society and patients, well heal gastritis, reduce The effect of treatment costs

Inactive Publication Date: 2015-04-15
唐桂益 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, for the treatment of upper gastrointestinal diseases related to Helicobacter pylori infection at home and abroad, Western medicine recommends triple therapy and quadruple therapy. The medication is complicated and expensive, which is contrary to the principle of clinical rational use of antibiotics, and can cause flora imbalance and bacterial resistance. medicine, many adverse reactions
At the same time, the high cost of treatment is unacceptable to people in developing countries and poor areas

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0008] 1. The preparation method of making granules from Artemisia annua

[0009] Crush and air-dry Artemisia annua, weigh it, add water and boil for 1 to 2 hours according to the weight ratio of Artemisia annua to water 1:4, filter out the dregs to obtain Artemisia annua decoction, concentrate the decoction in water to form ointment, add Equal amount of auxiliary agent dry powder, mixed evenly, dried, then pulverized into granules less than or equal to 60 meshes, packed and sealed into each bag containing 11.25g of Artemisia annua crude drug, made into a medicine for treating gastrointestinal diseases caused by Helicobacter pylori infection Granules.

[0010] 2. Clinical trial part

[0011] Patient selection: According to the "2010 National Guidelines for the Diagnosis and Treatment of Digestive Diseases" and "Helicobacter pylori Infection—Basic and Clinical" (Hunan Science and Technology Press, first edition in December 1997) Diagnostic criteria for Helicobacter pylori inf...

Embodiment 2

[0021] 1. The preparation method of decoction made from Artemisia annua

[0022] Crush and air-dry Artemisia annua, weigh it, add water and boil for 1 to 2 hours according to the weight ratio of Artemisia annua and water at 1:4, filter out the dregs to obtain Artemisia annua decoction, the amount is equivalent to 100 ml of crude drug containing Artemisia annua 22.5 grams, which is Qinghao decoction for the treatment of upper gastrointestinal tract diseases infected by Helicobacter pylori.

[0023] 2. Clinical trial part

[0024] Patient selection: According to the "2010 National Guidelines for the Diagnosis and Treatment of Digestive Diseases" and "Helicobacter pylori Infection—Basic and Clinical" (Hunan Science and Technology Press, first edition in December 1997) Diagnostic criteria for Helicobacter pylori infection. Select 76 cases of upper gastrointestinal tract patients with Helicobacter pylori infection, including 48 cases of chronic gastritis, 12 cases of gastric ulce...

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Abstract

The invention discloses an application of Artemisia carvifolia in the preparation of gastrointestinal disease treatment drugs, and belongs to the technical field of drugs. Artemisia carvifolia has the advantages of improvement of the symptoms of gastrointestinal diseases, lasting curative effect and no obvious untoward effects in the treatment of Helicobacter pylori infected gastrointestinal diseases, and is suitable for treating gastritis, gastric and duodenal ulcer or nausea, vomiting, abdominal pain, diarrhea and other diseases.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to the application of Artemisia annua in the preparation of medicine for treating human gastrointestinal diseases. Background technique [0002] According to the statistics of the World Health Organization, more than 10 million people die from gastrointestinal diseases in the world every year, and the threat of gastrointestinal diseases to human beings is shocking. Helicobacter pylori usually resides in the pylorus of the human stomach and is the chief culprit of gastrointestinal diseases. The western medicine names of gastrointestinal diseases in people infected by Helicobacter pylori mainly refer to chronic gastritis, gastric and duodenal ulcers, etc. In traditional Chinese medicine, the syndrome of stagnation and heat in the stomach refers to the main syndrome of epigastric pain and distension, and the secondary syndromes are poor appetite, belching, and pantothenic acid noise. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/282A61P31/04A61P1/04
CPCA61K36/282A61K9/0095
Inventor 唐桂益银春芬
Owner 唐桂益
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