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Composition with anti-acne effect and its application and preparation

A composition and acne technology, applied in the field of medicine, can solve problems such as unsatisfactory curative effect

Active Publication Date: 2017-10-10
BY HEALTH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But there are very few Chinese patent medicines for treating acne on the market at present, and the curative effect has not yet reached a satisfactory effect

Method used

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  • Composition with anti-acne effect and its application and preparation
  • Composition with anti-acne effect and its application and preparation
  • Composition with anti-acne effect and its application and preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Example 1 Test of acne removal effect

[0034] Test group: The test is divided into placebo group, single drug group, test group and control group. The single drug components are licorice single drug group, white peony single drug group, Danshen single drug group, and zinc citrate group; test components For test groups 1 to 5, test groups 1 to 5 ate combinations 1 to 5, and the formulas of combinations 1 to 5 are shown in Table 1. The control group ate a commercially available acne-removing capsule. The application scheme of each group is shown in Table 2.

[0035] Test method: 165 patients were selected for treatment in the dermatology department, all of whom were voluntary subjects with clinical acne Ⅰ-Ⅲ degree. They were randomly divided into 11 groups with 15 people in each group. The test group took the test product according to the recommended method and dosage, 750mg of oral drug per day, and the control group took the marketed product according to the recommended d...

Embodiment 2

[0064] Example 2 Preparation of anti-acne tablets

[0065] The formula of the anti-acne tablets is shown in Table 7:

[0066] Table 7 The formula of anti-acne tablets

[0067]

[0068] Technological operation of preparing anti-acne tablets:

[0069] Weigh the formula vitamin B 6 , Vitamin A, pre-gelatinized starch pre-mixed for 5 minutes; then with the formula amount of Danshen extract, Radix Paeoniae Alba extract, Licorice extract, zinc citrate, maltodextrin, crospovidone, high substituted hydroxypropyl Cellulose, silicon dioxide, and magnesium stearate are put into a mixer and mixed for 20-30 minutes.

[0070] Use a tablet press to compress the above-mentioned mixture into tablets, 1 g / tablet, to obtain plain tablets.

[0071] Weigh the formula amount of coating agent and water, configure them to an appropriate solid content, and stir in the paddle pan for 30 to 45 minutes; after the stirring is completed, coat the plain tablets until the surface is basically filmed and the color is c...

Embodiment 3

[0072] Example 3 Preparation of anti-acne capsules

[0073] The formula of anti-acne capsules is shown in Table 8:

[0074] Table 8 The formula of anti-acne capsules

[0075]

[0076] The technological operation of preparing anti-acne capsules:

[0077] Weighing: Accurately weigh various materials according to the above-mentioned formula and reserve.

[0078] Sieve: Put vitamin B 6 Pass through a 60-mesh sieve, and then together with vitamin A powder, gradually premix with part of the pregelatinized starch; zinc citrate through a 60-mesh sieve; each Chinese medicine extract through a 40-mesh sieve.

[0079] Total mixing: Put the prepared materials and the materials that have been premixed and sieved into the three-dimensional mixer for total mixing for 30 minutes, until the color is uniform, then discharge.

[0080] Filling: Use 0# mold to fill with 0.45g / capsule. During the filling process, control the difference of grain weight within ±4.5%, and check the appearance of the capsule at an...

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Abstract

The invention relates to the technical field of medicine, in particular to a composition with an acne-removing effect and its application and preparation. The composition is composed of licorice extract, white peony extract, salvia miltiorrhiza extract, zinc citrate, vitamin A and vitamin B6. The composition provided by the invention has remarkable acne-removing effect, can obviously reduce the amount of acne, and can obviously reduce the degree of skin lesions.

Description

Technical field [0001] The present invention relates to the technical field of medicine, in particular to a composition with acne-removing effect and its application and preparation. Background technique [0002] Acne, also known as acne, is a chronic inflammatory skin disease of the hair follicles and sebaceous glands that often occurs on the face and upper body. It is a common and frequently-occurring disease. The occurrence of acne is closely related to factors such as excessive sebum secretion, clogged hair follicle sebaceous duct, bacterial infection and inflammatory reaction. After entering puberty, the level of androgens, especially testosterone, in the human body rises rapidly, which promotes the development of sebaceous glands and produces a large amount of sebum. At the same time, the abnormal keratinization of the hair follicle sebaceous ducts causes the ducts to be blocked, the sebum discharge is obstructed, and the keratinous plugs or micro-acne are formed. A varie...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/71A23L33/105A23L33/15A23L33/155A23L33/12A61P17/10A61K31/07A61K31/4415A61K31/315A23L33/00
Inventor 邱春媚殷光玲黄远英王昌博
Owner BY HEALTH CO LTD