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Composition having efficacy of dispelling acnes as well as application and preparation of composition

A composition and acne technology, applied in the field of medicine, can solve problems such as unsatisfactory curative effect

Active Publication Date: 2015-06-03
BY HEALTH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But there are very few Chinese patent medicines for treating acne on the market at present, and the curative effect has not yet reached a satisfactory effect

Method used

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  • Composition having efficacy of dispelling acnes as well as application and preparation of composition
  • Composition having efficacy of dispelling acnes as well as application and preparation of composition
  • Composition having efficacy of dispelling acnes as well as application and preparation of composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Embodiment 1 Acne-removing effect test

[0034] Test grouping: the test is divided into placebo group, single drug group, test group and control group, among which the single drug group is licorice single drug group, white peony single drug group, Danshen single drug group, zinc citrate group; test components It is the test group 1-5, and the test group 1-5 eats the combination 1-5 respectively, and the formula of the combination 1-5 is shown in Table 1; the control group eats a commercially available acne-removing capsule. The dosage regimen of each group is shown in Table 2.

[0035] Test method: 165 cases of patients in the Department of Dermatology were selected, all of whom were voluntary subjects with clinical acne grades I-III. They were randomly divided into 11 groups with 15 people in each group. The trial group took the test product according to the recommended method and dosage, and took 750 mg of the drug orally every day. The control group took the commerci...

Embodiment 2

[0064] Example 2 Preparation of acne-removing tablets

[0065] The formula of acne-removing tablet is shown in Table 7:

[0066] Table 7 The formula of anti-acne tablets

[0067]

[0068] The technological operation of preparing acne-removing tablet:

[0069] Weigh the formula amount vitamin B 6 , vitamin A, pregelatinized starch premixed for 5 minutes; Cellulose, silicon dioxide, and magnesium stearate are put into a mixer and mixed for 20 to 30 minutes.

[0070] The above mixture is compressed into tablets with a tablet machine, 1 g / tablet, to obtain plain tablets.

[0071] Weigh the formula amount of coating agent and water, adjust to an appropriate solid content, and stir in a paddle pan for 30 to 45 minutes; after the stirring is completed, coat the plain tablet until the surface of the tablet is basically formed into a film and the color is consistent.

Embodiment 3

[0072] Example 3 Preparation of acne-removing capsules

[0073] The formula of Acne Removing Capsules is shown in Table 8:

[0074] Table 8 The formula of Acne Removing Capsules

[0075]

[0076] The technological operation of preparing acne-removing capsule:

[0077] Weighing: Accurately weigh various materials according to the above formula, and set aside.

[0078] Sieve: the vitamin B 6 Pass through a 60-mesh sieve, and then premix with vitamin A powder and part of the pregelatinized starch step by step; pass through a 60-mesh sieve for zinc citrate; pass through a 40-mesh sieve for each Chinese medicine extract.

[0079] Total mixing: Put the prepared materials and the pre-mixed and sieved materials into the three-dimensional mixer for 30 minutes and mix until the color is uniform, then discharge.

[0080] Filling: Use 0# mold to fill, and the filling capacity is 0.45g / capsule. During the filling process, control the grain weight difference within ±4.5%, and check t...

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PUM

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Abstract

The invention relates to the technical field of a medicine, and in particular relates to a composition having an efficacy of dispelling acnes as well as an application and a preparation of the composition. The composition consists of a liquorice extract, a white paeony root extract, a salvia miltiorrhiza extract, zinc citrate, vitamin A and vitamin B6. The composition disclosed by the invention has a significant effect of dispelling acnes, and the composition is capable of remarkably reducing the quantity of the acnes and significantly relieving the degree of skin lesion.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a composition with acne-removing effect and its application and preparation. Background technique [0002] Acne, also known as acne, is a chronic inflammatory skin disease of the pilosebaceous glands that occurs mainly on the face and upper body, and is a common frequently-occurring disease. The occurrence of acne is mainly closely related to factors such as excessive sebum secretion, pilosebaceous gland duct blockage, bacterial infection and inflammatory response. After entering puberty, the level of androgen in the human body, especially testosterone, increases rapidly, which promotes the development of sebaceous glands and produces a large amount of sebum. At the same time, abnormal keratinization of the pilosebaceous duct causes duct blockage, sebum discharge obstruction, and the formation of keratin plugs, that is, micropowder thorns. A variety of microorganisms in hair f...

Claims

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Application Information

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IPC IPC(8): A61K36/71A23L1/29A61P17/10A61K31/07A61K31/4415A61K31/315A23L33/00
Inventor 邱春媚殷光玲黄远英王昌博
Owner BY HEALTH CO LTD