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Traditional Chinese medicine for treating heat-toxin accumulation type traumatic chronic osteomyelitis and preparation method thereof

A technology of chronic osteomyelitis and accumulation type, applied in the field of medical preparations, can solve the problems of decreased curative effect, easy recurrence, drug resistance variation, etc., so as to reduce the recurrence rate and improve the therapeutic effect.

Inactive Publication Date: 2015-06-24
朱海颖
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the irrational use of antibiotics, pathogenic bacteria often have drug resistance and mutation, which reduces the curative effect
Although surgical treatment can remove the lesion, it has the disadvantage of easy recurrence

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0043] The present invention also provides the preparation method of above-mentioned Chinese medicine, and the dosage form of described Chinese medicine is capsule, and its preparation method comprises the following steps:

[0044] Step 1: Mix the raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 80-90% that is 3-5 times the mass of the mixture, heat and reflux for 1-2 hours, extract, and filter to obtain the first extract The dregs obtained by filtering are then added with 80-90% ethanol with an alcohol concentration of 2 to 3 times the quality of the dregs, heated and refluxed for 1 to 2 hours, extracted, and filtered to obtain a second extract; the first extract and The second extracts were combined, concentrated under reduced pressure to remove the ethanol solvent, and dried to obtain a dry paste;

[0045] The second step: place the dry paste obtained in the first step to pulverize in an ultrafine pulverizer for 1...

Embodiment 1

[0052] Embodiment 1 capsule

[0053] Take 60g of white hair rattan, 80g of pterygium, 180g of tree climbing dragon, 140g of copper hammer grass, 110g of plum blossom grass, 130g of blue skyflower, 70g of bald sore flower, 420g of bitter dish, 120g of Pinger grass, 90g of big fire grass root, share the head 160g of grass, 230g of cow horse vine, 140g of eight treasures, 80g of Polygonum vulgaris, 440g of martial arts vine, 170g of Shangshan dragon, 160g of Chuhu tiger and 210g of centipede vine;

[0054] Prepare as follows:

[0055] The first step: mix the raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 90% that is 4 times the mass of the mixture, heat and reflux for 2 hours, extract, and filter to obtain the first extract; filter the obtained dregs Then add ethanol with an alcohol concentration of 90% relative to the quality of the dregs, heat and reflux for 1 hour, extract, and filter to obtain the second extract;...

Embodiment 2

[0058] Embodiment 2 powder

[0059] Take 90g white hair rattan, 50g pterygium, 160g tree climbing dragon, 110g copper hammer grass, 150g plum flower grass, 140g blue skyflower, 90g bald sore flower, 440g bitter dish, 140g piner grass, 70g big fire grass root, share the head 180g of grass, 210g of cow horse vine, 120g of eight treasures of round leaves, 60g of Polygonum pubescens, 400g of martial boots vine, 150g of Shangshan dragon, 190g of Chuhu tiger and 230g of centipede vine.

[0060] Prepare as follows:

[0061] The first step: mix the various raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 75% that is 4 times the mass of the mixture, heat and reflux for 3 hours, extract, and filter to obtain the first extract; filter the obtained dregs Then add ethanol with an alcohol concentration of 75% that is twice the mass of the medicinal residues, heat and reflux for 2 hours, extract, and filter to obtain a second extr...

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PUM

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Abstract

The invention provides a traditional Chinese medicine for treating heat-toxin accumulation type traumatic chronic osteomyelitis and a preparation method thereof. The traditional Chinese medicine comprises the following raw materials: solanum lyratum thunb, pterocephalus hookeri, rhaphidophora decursiva, oxalis corymbosa, parnassia palustris, nervilia fordii, dicranostigma leptopodum, ixeris sonchifolia hance, ophioglossum petiolatum, anemone tomentosa root, herb of whiteflower violet, evergreen mucuna root and leaf, hylotelephium verticillatum, hairy knotweed herb, australian cowplant root or leaf, bodinier ampelopsis root-bark, geophila herbacea and creeping pothos. The traditional Chinese medicine can be used in combination with operative treatment and western medicine treatment to remarkably improve the treatment effect on heat-toxin accumulation type traumatic chronic osteomyelitis and effectively reduce the recurrence rate.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine for treating heat-toxin-accumulated traumatic chronic osteomyelitis and a preparation method thereof. Background technique [0002] Traumatic chronic osteomyelitis refers to chronic inflammation caused by bacterial infection and destruction of local bone tissue due to trauma or iatrogenic reasons. The disease is caused by various factors after trauma and develops due to improper treatment or delayed diagnosis and treatment. Patients may have chronic wasting symptoms such as weight loss and anemia. After the sinus tract is formed, it will not heal for a long time, and there will be discharge of purulent secretions, and sometimes small pieces of sequestrum will be discharged. In some cases, bone defects and fracture nonunions can be formed, and there is a certain rate of disability and malignant t...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61P31/04A61P19/08
Inventor 朱海颖赵国芹许莹
Owner 朱海颖
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