Lactobacillus rhamnosus with cholesterol-lowering effect and use thereof

Abstract

The invention provides a Lactobacillus rhamnosus with cholesterol-lowering effect and its application. If people consume too much high-cholesterol food, the synthesis and metabolism of cholesterol in the body will be overloaded, and the cholesterol in the blood will rise, which will cause the precipitation of cholesterol on the arterial wall, and induce the occurrence of cardiovascular and other diseases such as arteriosclerosis. Highly active strain obtained through isolation, purification, physical mutagenesis, and optimization in naturally fermented soybean products. Mycological classification name: Lactobacillus rhamnosus SCF 20120718. Bacterial characteristics: cultured in the culture medium of a constant temperature incubator at 37°C, it was found that when the dilution concentration was 10‑5, the bacteria grew better and the colonies were dispersed. Under the same conditions, the colonies grow in different sizes. The colonies are round, milky white, with neat edges and smooth surface. The smaller colonies are yellowish. The preservation number is: CGMCC No.7085. The invention provides the probiotic functional health product raw material for preventing and treating cardiovascular and cerebrovascular diseases.

Description

Technical field: [0001] The invention relates to a kind of Lactobacillus rhamnosus (Lactobacillus rhamnosus) SCF20120718 obtained through optimization, which can be used for fermenting and preparing soybean milk with cholesterol-lowering effect and related health products and medicines. Background technique: [0002] Cholesterol in the human body usually exists in cells and tissues in the form of free and cholesteryl esters, and is highly distributed in the brain and nerve tissues, kidneys, skin, liver and bile. It is an important component of the internal membrane structure and participates in the formation of Biomembrane also plays an important role in the process of plasma lipoprotein synthesis, lipid metabolism, and nerve excitation transmission, and is also the raw material for the synthesis of bile acid, vitamin D, and various hormones. Therefore, cholesterol is indispensable for maintaining the body's physiological functions important substance. However, while choles...

AI Technical Summary

Problems solved by technology

However, while cholesterol plays an important role in the body, if it is too high in the body, especially in the blood, it will also cause certain harm, affect metabolism, and induce cancer; it can also cause cardiovascular endothelial cell dysfunction, especially low-density lipoprotein If it is too high, it will affect the abnormal regulation of calcium ions, which is a cardiovascular dysfunction, leading to cardiovascular and cerebrovascular damage and disease occurrence.

may also induce dementia

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