Lactobacillus rhamnosus having cholesterol lowering effect, and uses thereof

Abstract

The present invention provides Lactobacillus rhamnosus having a cholesterol lowering effect, and uses thereof. In the prior art, if people uptakes too high high-cholesterol foods, the synthesis and the metabolism of the cholesterol in the body overload, and the blood cholesterol rises so as to cause generation of cholesterol precipitation on the artery vessel, and induction of atherosclerosis and other cardiovascular diseases. According to the present invention, the high activity strain is collected from the naturally-fermented soybean product and is obtained through separation, purification, physical mutation and preferable selection, the mycology classification name is Lactobacillus rhamnosus SCF 20120718, the mycology characteristics comprise that: the bacteria growth is good and the colonies are dispersed when the dilution concentration is 10<-5> after the bacterial are culture in a culture medium in a 37 DEG C constant temperature incubator, the growing colonies have characteristics of different sizes, round shape, milk white color, neat edges and smooth surface under the same conditions, and the small colonies have the slight-yellow color, and the preservation number is CGMCC No.7085. The present invention provides the probiotic functional health product raw materials for prevention and treatment of cardiovascular and cerebrovascular diseases.

Description

Technical field: [0001] The invention relates to a kind of Lactobacillus rhamnosus (Lactobacillus rhamnosus) SCF 20120718 obtained through optimization, which can be used for fermenting and preparing soybean milk with cholesterol-lowering effect and related health products and medicines. Background technique: [0002] Cholesterol in the human body usually exists in cells and tissues in the form of free and cholesteryl esters, and is highly distributed in the brain and nerve tissues, kidneys, skin, liver and bile. It is an important component of the internal membrane structure and participates in the formation of Biomembrane also plays an important role in the process of plasma lipoprotein synthesis, lipid metabolism, and nerve excitation transmission, and is also the raw material for the synthesis of bile acid, vitamin D, and various hormones. Therefore, cholesterol is indispensable for maintaining the body's physiological functions important substance. However, while chole...

AI Technical Summary

Problems solved by technology

However, while cholesterol plays an important role in the body, if it is too high in the body, especially in the blood, it will also cause certain harm, affect metabolism, and induce cancer; it can also cause cardiovascular endothelial cell dysfunction, especially low-density lipoprotein If it is too high, it will affect the abnormal regulation of calcium ions, which is a cardiovascular dysfunction, leading to cardiovascular and cerebrovascular damage and disease occurrence.

may also induce dementia

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